Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMZF5XI)

Drug Name

Biphenyl mannoside derivative 11 Drug Info

Synonyms

PMID26651364-Compound-35

Indication

Disease Entry	ICD 11	Status	REF
Crohn disease	DD70	Patented	[1]
Ulcerative colitis	DD71	Patented	[1]
Urinary tract infection	GC08	Patented	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Patented Agent(s)

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Drug(s) Targeting Bacterial Fimbrin D-mannose adhesin (Bact FimH)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
EB8018	DM753H8	Crohn disease	DD70	Phase 2	[2]
GSK3882347	DM1DU20	Urinary tract infection	GC08	Phase 1	[3]
GSK3882347	DM1DU20	Urinary tract infection	GC08	Phase 1	[4]
Biaryl mannoside derivative 24	DMF5TB4	Crohn disease	DD70	Patented	[1]
PMID26651364-Compound-5	DMH7XL3	Crohn disease	DD70	Patented	[1]
PMID26651364-Compound-116	DMJ3201	Crohn disease	DD70	Patented	[1]
Biaryl mannoside derivative 8	DMWF2VG	Crohn disease	DD70	Patented	[1]
Beta-cyclodextrin conjugate derivative 3	DMQJF4P	Crohn disease	DD70	Patented	[1]
PMID26651364-Compound-109	DM01IWV	Crohn disease	DD70	Patented	[1]
PMID26651364-Compound-114	DM5GHJA	Crohn disease	DD70	Patented	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bacterial Fimbrin D-mannose adhesin (Bact FimH)	TTTCRU2	FIMH_ECOLI	Antagonist	[1]

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References

1	Mannose-derived FimH antagonists: a promising anti-virulence therapeutic strategy for urinary tract infections and Crohn's disease.Expert Opin Ther Pat. 2016;26(2):175-97.
2	Clinical pipeline report, company report or official report of Enterome Biosciences.
3	Clinical pipeline report, company report or official report of Fimbrion Therapeutics
4	Clinical pipeline report, company report or official report of GlaxoSmithKline