Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMZVEN0)

Drug Name

GSK3965193 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Hepatitis B	1E51	Phase 1	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Terminal nucleotidyltransferase 4A (TENT4A)	TT0XZ4Q	PAPD7_HUMAN	Inhibitor	[2]
Terminal nucleotidyltransferase 4B (TENT4B)	TTB5R6M	PAPD5_HUMAN	Inhibitor	[2]

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References

1	ClinicalTrials.gov (NCT05330455) Four-part, Randomized, Double-blind (Parts 1, 2A, 3 and 4), Multi-center, Placebo-controlled Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK3965193 Monotherapy in Healthy Participants and in Participants Living With Chronic Hepatitis B Infection; and GSK3965193 in Combination With Bepirovirsen in Participants Living With Chronic Hepatitis B Infection. U.S.National Institutes of Health.
2	Clinical pipeline report, company report or official report of GlaxoSmithKline