Details of the Drug Reposition

General Information of This Drug (ID: DM1D8XY)

• Drug Name: Dantrolene (DM1D8XY)
• Synonyms: Dantrium; Dantroleno; Dantrolenum; DANTROLENE SODIUM; Dantrium Intravenous; Dantrium (TN); Dantrolen (TN); Dantroleno [INN-Spanish]; Dantrolenum [INN-Latin]; F-368; Dantrolene (USAN/INN); Dantrolene [USAN:BAN:INN]; 1-(((5-(4-Nitrophenyl)-2-furanyl)methylene)amino)-2,4-imidazolidinedione; 1-((5-(p-Nitrophenyl)furfurylidene)amino)hydantoin; 1-({(1E)-[5-(4-nitrophenyl)furan-2-yl]methylidene}amino)imidazolidine-2,4-dione; 1-({[5-(4-nitrophenyl)furan-2-yl]methylidene}amino)imidazolidine-2,4-dione; 1-[(E)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]imidazolidine-2,4-dione
• Therapeutic Class: Muscle Relaxants
• Drug Type: Small molecular drug

Information on Drug Reposition of This Drug

1 Discontinued in Phase 3 Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Muscle spasm	DISNGQVY	MB47.3	Discontinued in Phase 3	[1]

1 Discontinued in Phase 2 Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Malignant hyperthermia of anesthesia	DISYC9XI	N.A.	Discontinued in Phase 2	[2]

1 Investigative Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Hyperthermia	DISU7VUO	MG26	Investigative	[3]

References

• [1] Imatinib Mesylate Treatment of Patients With Malignant Peripheral Nerve Sheath Tumors
• [2] ClinicalTrials.gov (NCT01652014) Single or Double Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Hematologic Malignancies
• [3] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4172).