Details of the Drug Reposition

General Information of This Drug (ID: DM8QB1D)

Drug Name
Olaparib   DM8QB1D
Synonyms
AZD 2281; AZD2281; AZD-2281; Acylpiperazine analogue, 47; KU-0059436; KU-59436; Olaparib, KU-0059436, AZD2281,KU0059436, AZD2281; 4-[(3-{[4-Cyclopropylcarbonyl)piperazin-4-yl]carbonyl}-4-fluorophenyl)methyl]phtalazin-1(2H)-one; 4-[3-(4-Cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)
1 Approved Indication(s)
Indication Name Indication ID ICD-11 Status REF
Ovarian cancer DISZJHAP 2C73 Approved [1]
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2 Phase 3 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Pancreatic cancer DISJC981 2C10 Phase 3 [2]
Prostate cancer DISF190Y 2C82.0 Phase 3 [2]
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1 Withdrawn Indication(s)
Indication Name Indication ID ICD-11 Status REF
Peritoneal cancer DISYX23I 2C51.Z Withdrawn [3]
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1 Discontinued in Phase 1 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Ovarian epithelial tumor DISTAI0X N.A. Discontinued in Phase 1 [4]
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References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7519).
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 Statins To Treat Adult Cystic Fibrosis
4 ZD6474 Alone and in Combination With Retinoic Acid in Pediatric Neuroblastoma