Details of the Drug Reposition

General Information of This Drug (ID: DMKOXFE)

• Drug Name: Doxylamine (DMKOXFE)
• Synonyms: Dossilamina; Doxilamina; Doxilminio; Doxylaminum; Dossilamina [DCIT]; Diclectin (TN); Dolased (TN); Donormyl (TN); Dormidina (TN); Doxilminio [INN-Spanish]; Doxylamine (INN); Doxylamine [INN:BAN]; Doxylaminum [INN-Latin]; Dozile (TN); Evanorm (TN); Mersyndol (TN); Restavit (TN); Somnil (TN); Syndol (TN); Unisom-2 (TN); Phenyl-2-pyridylmethyl-beta-N,N-dimethylaminoethyl ether; N,N-Dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)ethanamine; N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine; N,N-dimethyl-2-[(1-phenyl-1-pyridin-2-ylethyl)oxy]ethanamine; N,N-dimethyl-2-[1-phenyl-1-(pyridin-2-yl)ethoxy]ethanamine; 2-(alpha-(2-(Dimethylamino)ethoxy)-alpha-methylbenzyl)pyridine; 2-Dimethylaminoethoxyphenylmethyl-2-picoline
• Therapeutic Class: Hypnotics and Sedatives
• Drug Type: Small molecular drug

Information on Drug Reposition of This Drug

3 Approved Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Common cold	DIS3MADM	CA00	Approved	[1]
Vasomotor/allergic rhinitis	DISHSTQ0	CA08	Approved	[1]
Urticaria	DIS9WQAI	EB00-EB05	Approved	[1]

1 Withdrawn Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Allergic conjunctivitis	DISZ5ZJN	9A60.02	Withdrawn	[2]

2 Investigative Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Pruritus	DISVH62W	EC90	Investigative	[1]
Morning sickness	DISVCIJW	SC00	Investigative	[3]

References

• [1] Doxylamine FDA Label
• [2] ClinicalTrials.gov (NCT00598858) Neoadjuvant Docetaxel on Newly Diagnosed Intermediate and High Grade Cancer of the Prostate
• [3] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7171).