Details of the Drug Reposition

General Information of This Drug (ID: DMKSFPE)

Drug Name
BMS 275291   DMKSFPE
Synonyms
D 2163; N-((2S)-2-Mercapto-1-oxo-4-(3,4,4-trimethyl-2,5-dioxo-1-imidazolidinyl)butyl)-L-leucyl-N,3-dimethyl-L-valinamide; (2S)-N-[(2S)-3,3-dimethyl-2-(methylamino)butanoyl]-4-methyl-2-[[(2S)-2-sulfanyl-4-(3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)butanoyl]amino]pentanamide
Therapeutic Class
Anticancer Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)
3 Discontinued in Phase 3 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Kaposi sarcoma DISC1H1Z 2B57 Discontinued in Phase 3 [1]
Non-small-cell lung cancer DIS5Y6R9 2C25.Y Discontinued in Phase 3 [1]
Prostate cancer DISF190Y 2C82.0 Discontinued in Phase 3 [1]
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References

1 Phase 1/2 trial of BMS-275291 in patients with human immunodeficiency virus-related Kaposi sarcoma: a multicenter trial of the AIDS Malignancy Consortium. Cancer. 2008 Mar 1;112(5):1083-8.