Details of the Drug Reposition

General Information of This Drug (ID: DMMZXIW)

Drug Name
Rabeprazole   DMMZXIW
Synonyms
Dexrabeprazole; Eraloc; Rebeprazole sodium; CL23619; LY307640; Aciphex (TN); Eraloc (TN); Pariet (TN); Rabeprazole (INN); Rabeprazole [BAN:INN]; Rabeprazole [INN:BAN]; Rablet (TN); 2-(((4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole; 2-((4-(3-methoxypropoxy)-3-methylpyridin-2-yl)methylsulfinyl)-1H-benzimidazole; 2-({[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methyl}sulfinyl)-1H-benzimidazole; 2-[[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methylsulfinyl]-1H-benzimidazole
Therapeutic Class
Antiulcer Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)
3 Approved Indication(s)
Indication Name Indication ID ICD-11 Status REF
Bacterial infection DIS5QJ9S 1A00-1C4Z Approved [1]
Gastrinoma DIS4IMNF 2C10.1 Approved [2]
Peptic ulcer DISL8XZI DA61 Approved [2]
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1 Withdrawn Indication(s)
Indication Name Indication ID ICD-11 Status REF
Multiple endocrine neoplasia DISZGBKW N.A. Withdrawn [3]
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2 Discontinued in Phase 3 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Gastroesophageal reflux disease DISQ8G5S DA22.Z Discontinued in Phase 3 [4]
Duodenal ulcer DISNHHCN DA63 Discontinued in Phase 3 [5]
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1 Discontinued in Phase 2 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Systemic mastocytosis DISNQ2OY 2A21.0 Discontinued in Phase 2 [6]
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References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7290).
2 Rabeprazole FDA Label
3 Gemcitabine Hydrochloride and Cisplatin or High-Dose Methotrexate, Vinblastine, Doxorubicin Hydrochloride, and Cisplatin in Treating Patients With Urothelial Cancer
4 Effect of Ranolazine on Gastrointestinal Motor Function and Pain in Patients With IBS-D
5 Study of Nitazoxanide in the Treatment of Clostridium Difficile-associated Disease
6 Sitagliptin in Cystic Fibrosis-Related Diabetes