Details of the Drug Reposition | DrugMAP

General Information of This Drug (ID: DMNC1AS)

Drug Name	INZ-701 DMNC1AS
Drug Type	Enzyme replacement

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)

2 Phase 1/2 Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Hypophosphatemic rickets	DIS7XTW5	5C63.22	Phase 1/2	[1]
Pseudoxanthoma elasticum	DIS8WUQG	EC40	Phase 1/2	[2]
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References

1	ClinicalTrials.gov (NCT04686175) A Phase 1/2, Open-Label, Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INZ-701 Followed by an Open-Label Long-Term Extension Period in Adults With ENPP1 Deficiency. U.S.National Institutes of Health.
2	ClinicalTrials.gov (NCT05030831) A Phase 1/2, Open-Label, Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INZ-701 Followed by an Open-Label Long-Term Extension Period in Adults With ABCC6 Deficiency Manifesting as Pseudoxanthoma Elasticum (PXE). U.S.National Institutes of Health.