Details of the Drug

General Information of Drug (ID: DMNC1AS)

Drug Name
INZ-701
Indication
Disease Entry ICD 11 Status REF
Hypophosphatemic rickets 5C63.22 Phase 1/2 [1]
Pseudoxanthoma elasticum EC40 Phase 1/2 [2]
Drug Type
Enzyme replacement
Cross-matching ID
TTD ID
DK0B7G
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1) TTZTIWS ENPP1_HUMAN Replacement [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT04686175) A Phase 1/2, Open-Label, Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INZ-701 Followed by an Open-Label Long-Term Extension Period in Adults With ENPP1 Deficiency. U.S.National Institutes of Health.
2 ClinicalTrials.gov (NCT05030831) A Phase 1/2, Open-Label, Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INZ-701 Followed by an Open-Label Long-Term Extension Period in Adults With ABCC6 Deficiency Manifesting as Pseudoxanthoma Elasticum (PXE). U.S.National Institutes of Health.
3 Clinical pipeline report, company report or official report of Inozyme pharma