Details of the Drug Reposition

General Information of This Drug (ID: DMSTHG1)

Drug Name	VX-371 DMSTHG1

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)

2 Phase 2 Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Cystic fibrosis	DIS2OK1Q	CA25	Phase 2	[1]
Primary ciliary dyskinesia	DISOBC7V	LA75.Y	Phase 2	[2]
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References

1	ClinicalTrials.gov (NCT02709109) A Study to Evaluate the Safety and Efficacy of VX-371 in Subjects With Cystic Fibrosis Who Are Homozygous for the F508del-CFTR Mutation. U.S. National Institutes of Health.
2	ClinicalTrials.gov (NCT02871778) Clearing Lungs With ENaC Inhibition in Primary Ciliary Dyskinesia (CLEAN-PCD). U.S. National Institutes of Health.