Details of the Drug

General Information of Drug (ID: DM0I5LM)

Drug Name

DdRNAi therapy rHIV7-shl-TAR-CCR5RZ, stem cells

Synonyms

BLT-HIV; Lentiviral vector delivered DNA-directed RNAi therapeutic (HIV infection), Benitec; RHIV7-shl-TAR-CCR5RZ; T-cell therapy (HIV infection), Benitec; Lentiviral vector delivered DNA-directed RNAi therapeutic (HIV-associated lymphoma), Benitec; DdRNAi therapy (rHIV7-shl-TAR-CCR5RZ, T-cells, HIV), Benitec; DdRNAi therapy (rHIV7-shl-TAR-CCR5RZ, stem cells, HIV/lymphoma), Benitec

Indication

Disease Entry	ICD 11	Status	REF
Human immunodeficiency virus infection	1C62	Phase 1/2	[1]
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Drug Type

RNAi therapeutics

Cross-matching ID

TTD ID: D0O4RB

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
CCR5 messenger RNA (CCR5 mRNA)	TTJIH8Q	CCR5_HUMAN	Not Available	[2]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Clinical pipeline report, company report or official report of Benitec Ltd.
2	Progress on RNAi-based molecular medicines. Int J Nanomedicine. 2012; 7: 3971-3980.