Details of the Drug

General Information of Drug (ID: DM0QZJX)

Drug Name
JNJ-55308942
Indication
Disease Entry ICD 11 Status REF
Anhedonia MB24.2 Phase 1 [1]
Mood disorder 6A60-6E23 Phase 1 [2]
Neuroinflammation 1D0Y Phase 1 [1]
Cross-matching ID
PubChem CID
90408860
TTD ID
D0OQ1A
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
P2X purinoceptor 7 (P2RX7) TT473XN P2RX7_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Anhedonia
ICD Disease Classification MB24.2
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
P2X purinoceptor 7 (P2RX7) DTT P2RX7 1.11E-06 0.37 0.49
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Antibodies and venom peptides: new modalities for ion channels. Nat Rev Drug Discov. 2019 May;18(5):339-357.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)