General Information of Drug (ID: DM0ZMNI)

Drug Name
REGN6569
Indication
Disease Entry ICD 11 Status REF
Squamous head and neck cell carcinom 2D60.0 Phase 1 [1]
Drug Type
Antibody
Cross-matching ID
TTD ID
D8CFX3

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Activation-inducible TNFR family receptor (TNFRSF18) TTG6LA7 TNR18_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Squamous head and neck cell carcinom
ICD Disease Classification 2D60.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Activation-inducible TNFR family receptor (TNFRSF18) DTT TNFRSF18 2.39E-03 -0.54 -0.7
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT04465487) Study of REGN6569 and Cemiplimab in Adult Patients With Advanced Solid Tumor Malignancies. U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of Regeneron Pharmaceuticals.