Details of the Drug

General Information of Drug (ID: DM129VT)

Drug Name

514G3

Indication

Disease Entry	ICD 11	Status	REF
Staphylococcus infection	1B5Y	Phase 1/2	[1]
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Drug Type

Antibody

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Staphylococcus IgG binding protein A (Stap-coc SpA)	TTOWKQ9	SPA_STAA8	Inhibitor	[2]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT02357966) A Study of the Safety and Efficacy of 514G3 in Subjects Hospitalized With Bacteremia Due to Staphylococcus Aureus. U.S. National Institutes of Health.
2	A natural human monoclonal antibody targeting Staphylococcus Protein A protects against Staphylococcus aureus bacteremia. PLoS One. 2018 Jan 24;13(1):e0190537.