Details of the Drug

General Information of Drug (ID: DM1MGBX)

Drug Name

Alpha-Helical lipopeptides IIS

Synonyms

IIS

Indication

Disease Entry	ICD 11	Status	REF
Middle East Respiratory Syndrome (MERS)	1D64	Preclinical	[1]
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Therapeutic Class

Antiviral Agents

Drug Type

Protein/peptide drug

Sequence

IEEISKKIEEISKKIEEISKKIEEISKKIEEISKK-A-K(C16)

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
MERS-CoV spike glycoprotein (S)	TT85VHW	A0A140AYZ5_9BETC	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	De Novo Design of -Helical Lipopeptides Targeting Viral Fusion Proteins: A Promising Strategy for Relatively Broad-Spectrum Antiviral Drug Discovery. J Med Chem. 2018 Oct 11;61(19):8734-8745.