Details of the Drug

General Information of Drug (ID: DM1O2X6)

Drug Name

KPG-818

Indication

Disease Entry	ICD 11	Status	REF
Systemic lupus erythematosus	4A40.0	Phase 1	[1]
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Drug Type

Small molecular drug

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Cerebron E3 ubiquitin ligase complex (CRL4-CRBN E3 ubiquitin ligase)	TTEZQ39	CUL4A_HUMAN/CUL4B_HUMAN-DDB1_HUMAN-CRBN_HUMAN	Modulator	[2]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT04643067) A Study to Assess the Safety and Tolerability, PK and Efficacy of KPG-818 in Mild to Moderate SLE Patients (Lupus). U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of Kangpu Biopharmaceuticals.