Details of the Drug

General Information of Drug (ID: DM1Q18V)

Drug Name

MK-7622

Synonyms

M1 receptor modulator; 1227923-29-6; MK-7622; MK7622; MK 7622; 3-[(1S,2S)-2-Hydroxycyclohexyl]-6-[(6-methyl-3-pyridinyl)methyl]benzo[h]quinazolin-4(3H)-one; SCHEMBL2399084; EX-A804; JUVQLZBJFOGEEO-GOTSBHOMSA-N; BCP27739; ZINC95930184; AKOS028113668; DB12897; CS-5442; HY-15618; Benzo(H)quinazolin-4(3H)-one, 3-((1S,2S)-2-hydroxycyclohexyl)-6-((6-methyl-3-pyridinyl)methyl)-; AS-35236; KB-145903; J-690076; UNII-57R7D1Q49R component JUVQLZBJFOGEEO-GOTSBHOMSA-N

Indication

Disease Entry	ICD 11	Status	REF
Alzheimer disease	8A20	Phase 2	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C25H25N3O2
Canonical SMILES: CC1=NC=C(C=C1)CC2=CC3=C(C4=CC=CC=C42)N=CN(C3=O)C5CCCCC5O
InChI: 1S/C25H25N3O2/c1-16-10-11-17(14-26-16)12-18-13-21-24(20-7-3-2-6-19(18)20)27-15-28(25(21)30)22-8-4-5-9-23(22)29/h2-3,6-7,10-11,13-15,22-23,29H,4-5,8-9,12H2,1H3/t22-,23-/m0/s1
InChIKey: JUVQLZBJFOGEEO-GOTSBHOMSA-N

Cross-matching ID

PubChem CID: 46207733
CAS Number: 1227923-29-6
TTD ID: D02WFN

References

1	ClinicalTrials.gov (NCT01852110) Efficacy and Safety of MK-7622 as Adjunct Therapy in Participants With Alzheimer's Disease (MK-7622-012). U.S. National Institutes of Health.