Details of the Drug

General Information of Drug (ID: DM1W8Y0)

Drug Name

LG-888

Synonyms

Coagulation stimulator (factor VIII deficiency, protein recombinant), Lentigen; Factor VIII agonist (factor VIII deficiency, protein chimeric), Lentigen

Indication

Disease Entry	ICD 11	Status	REF
Factor VIII deficiency	3B10	Investigative	[1]
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Cross-matching ID

TTD ID: D0Q7XA

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Coagulation factor VIII (F8)	TT1290U	FA8_HUMAN	Stimulator	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

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Molecular Expression Atlas of This Drug

The Studied Disease

Factor VIII deficiency

ICD Disease Classification

3B10

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Coagulation factor VIII (F8)	DTT	F8	1.08E-22	0.89	1.82

Molecular Expression Atlas (MEA)

MEA Detail

Jump to Detail Molecular Expression Atlas of This Drug

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2607).