Details of the Drug

General Information of Drug (ID: DM263RP)

Drug Name
BIIB092
Indication
Disease Entry ICD 11 Status REF
Progressive supranuclear palsy 8A00.10 Phase 2 [1]
Alzheimer disease 8A20 Phase 1 [2]
Cross-matching ID
TTD ID
D0I8FS
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Microtubule-associated protein tau (MAPT) TTS87KH TAU_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Progressive supranuclear palsy
ICD Disease Classification 8A00.10
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Microtubule-associated protein tau (MAPT) DTT MAPT 3.76E-06 -0.22 -0.6
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT03068468) Study of BIIB092 in Participants With Progressive Supranuclear Palsy (PASSPORT). U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)