Details of the Drug

General Information of Drug (ID: DM2PVLH)

Drug Name

MGA271

Indication

Disease Entry	ICD 11	Status	REF
Metastatic cancer	2D50-2E2Z	Phase 1	[1]
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Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Metastatic cancer

ICD Disease Classification

2D50-2E2Z

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
B7 homolog 3 (CD276)	DTT	CD276	3.92E-01	-0.04	-0.81
B7 homolog 3 (CD276)	DTT	CD276	7.33E-02	-0.53	-1.33

Molecular Expression Atlas (MEA)

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References

1	ClinicalTrials.gov (NCT01918930) Tissue Procurement Substudy for Participants in Study CP-MGA271-01. U.S. National Institutes of Health.
2	T Cell Coinhibition and Immunotherapy in Human Breast Cancer. Discov Med. 2012 October; 14(77): 229-236.