Details of Disease

General Information of Disease (ID: DISBPS35)

Disease Name Metastatic cancer
Disease Class 2D50-2E2Z: Metastatic tumour
Disease Hierarchy
DIS01GPL: Grass pollen hypersensitivity
DISBPS35: Metastatic cancer
ICD Code
ICD-11
ICD-11: 2D50-2E2Z
ICD-10
ICD-10: C64-C68
ICD-9
ICD-9: 188, 189
Expand ICD-9
188189

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 7 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
MLN1202 DM24SOL Phase 2 Small molecular drug [1]
CAR-T Cells targeting EpCAM DMREQCF Phase 1/2 CAR T Cell Therapy [2]
ETBX-011 cancer vaccine DMQFDMH Phase 1/2 NA [3]
LOR 253 DMPD7CW Phase 1 NA [4]
LY2624587 DM289Z4 Phase 1 Antibody [5]
MGA271 DM2PVLH Phase 1 NA [6]
TSR-042 DM56PFL Phase 1 Monoclonal antibody [7]
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⏷ Show the Full List of 7 Drug(s)
This Disease is Treated as An Indication in 99 Patented Agent(s)
Drug Name Drug ID Highest Status Drug Type REF
1,2-dihydroindazolo[4,3-bc][1,5]benzoxazepine derivative 1 DMRFXMB Patented Small molecular drug [8]
Benzimidazole and imidazopyridine derivative 1 DMIXERP Patented Small molecular drug [8]
Benzonaphthyridine derivative 1 DMM9J34 Patented Small molecular drug [8]
Benzonaphthyridine derivative 2 DMB74LZ Patented Small molecular drug [8]
Bis-indolylmaleimide derivative 1 DMOR9ZA Patented Small molecular drug [8]
Dibenzo [c,f]-[2,7]naphthyridine derivative 1 DMRM5I1 Patented Small molecular drug [8]
Heteroaryl-carboxamide derivative 1 DMPRF1K Patented NA [8]
Heteroaryl-carboxamide derivative 10 DMVTARK Patented NA [8]
Heteroaryl-carboxamide derivative 2 DMGEFIW Patented NA [8]
Heteroaryl-carboxamide derivative 3 DMBGTNM Patented NA [8]
Heteroaryl-carboxamide derivative 4 DMHUIXR Patented NA [8]
Heteroaryl-carboxamide derivative 5 DMMX6V4 Patented NA [8]
Heteroaryl-carboxamide derivative 6 DM9IPDU Patented NA [8]
Heteroaryl-carboxamide derivative 7 DMOAYEV Patented NA [8]
Heteroaryl-carboxamide derivative 8 DMJTN91 Patented NA [8]
Heteroaryl-carboxamide derivative 9 DMI627Z Patented NA [8]
Heterocyclic derivative 10 DMN580F Patented NA [8]
Heterocyclic derivative 11 DMUOI92 Patented NA [8]
Heterocyclic derivative 12 DMQJW9R Patented NA [8]
Heterocyclic derivative 13 DMWOBHM Patented NA [8]
Heterocyclic derivative 14 DMJ0WVR Patented NA [8]
Heterocyclic derivative 15 DMWZNDO Patented NA [8]
Heterocyclic derivative 16 DM6NJV7 Patented NA [8]
Heterocyclic derivative 17 DMD1K7E Patented NA [8]
Heterocyclic derivative 18 DMFUEDL Patented NA [8]
Heterocyclic derivative 19 DMNG0WH Patented NA [8]
Heterocyclic derivative 4 DM7VP8M Patented NA [8]
Heterocyclic derivative 5 DMWJDEO Patented NA [8]
Heterocyclic derivative 6 DM6HWN3 Patented NA [8]
Heterocyclic derivative 7 DMU6LS4 Patented NA [8]
Heterocyclic derivative 8 DMKPSIA Patented NA [8]
Heterocyclic derivative 9 DMY4LB7 Patented NA [8]
Heterocyclic-carboxamide derivative 1 DMA91IJ Patented Small molecular drug [8]
Heterocyclic-carboxamide derivative 2 DMSQK50 Patented Small molecular drug [8]
Imidazo quinoline derivative 1 DMGDMWA Patented Small molecular drug [8]
Indazole derivative 1 DME8JTW Patented Small molecular drug [8]
Indolinone derivative 1 DMTC129 Patented Small molecular drug [8]
PMID25684022-Compound-EP20041486488 DMDZT7Y Patented Small molecular drug [8]
PMID25684022-Compound-US20120277229 39(1.1) DMR4MSH Patented NA [8]
PMID25684022-Compound-US20120277229 40(1.2) DMR3J9A Patented NA [8]
PMID25684022-Compound-US20120277229 41(1.3) DM7V6E0 Patented NA [8]
PMID25684022-Compound-US20120277229 44(1.4) DMUQ04C Patented NA [8]
PMID25684022-Compound-US20120277229 45(1.5) DMEIA6Y Patented NA [8]
PMID25684022-Compound-US20130053382 35(1-11) DMDHJMU Patented NA [8]
PMID25684022-Compound-US20130053382 36(3-5) DM40FVN Patented NA [8]
PMID25684022-Compound-US20130053382 37(4-6) DMY7Z85 Patented NA [8]
PMID25684022-Compound-US20130053382 38(5-7) DMHLQ2T Patented NA [8]
PMID25684022-Compound-WO2004087707 DM809AX Patented Small molecular drug [8]
PMID25684022-Compound-WO2006015124 DMV7PNF Patented Small molecular drug [8]
PMID25684022-Compound-WO2008005457 DMDMJYL Patented Small molecular drug [8]
PMID25684022-Compound-WO2008079988 DMKJ1HC Patented Small molecular drug [8]
PMID25684022-Compound-WO2008107444 DM8L5JR Patented Small molecular drug [8]
PMID25684022-Compound-WO2009153313 DMTP02Q Patented Small molecular drug [8]
PMID25684022-Compound-WO2010127754 DM37FDV Patented Small molecular drug [8]
PMID25684022-Compound-WO2011137219 35(1-11) DM3IZ0H Patented NA [8]
PMID25684022-Compound-WO2011137219 36(3-5) DMAQHI5 Patented NA [8]
PMID25684022-Compound-WO2011137219 37(4-6) DMSQ5J8 Patented NA [8]
PMID25684022-Compound-WO2011137219 38(5-7) DM4NXBK Patented NA [8]
PMID25684022-Compound-WO2012135799 42(1.4) DMSDRA4 Patented NA [8]
PMID25684022-Compound-WO2012135799 43(1.5) DMHI3O1 Patented NA [8]
PMID27998201-Compound-11 DMTV5NU Patented Small molecular drug [9]
Pyrazole derivative 61 DMO6M1Q Patented Small molecular drug [8]
Pyrazolopyridines and imidazopyridine derivative 1 DMSR5FO Patented Small molecular drug [8]
Pyridinone carboxamide derivative 1 DM3F4KS Patented Small molecular drug [8]
Pyrido[4,3-d]pyrimidin-5(6H)-one derivative 1 DMOTGEK Patented Small molecular drug [8]
Pyrimidine derivative 3 DMC3E8M Patented Small molecular drug [8]
Pyrimidinone derivative 1 DM1I7Z6 Patented Small molecular drug [8]
Thiazole carboxamide derivative 1 DMW62LX Patented NA [8]
Thiazole carboxamide derivative 10 DMWKI89 Patented NA [8]
Thiazole carboxamide derivative 11 DM0Q3HF Patented NA [8]
Thiazole carboxamide derivative 12 DMG0H73 Patented NA [8]
Thiazole carboxamide derivative 13 DMHQCEJ Patented NA [8]
Thiazole carboxamide derivative 14 DMMKNP7 Patented NA [8]
Thiazole carboxamide derivative 15 DMCH1DL Patented NA [8]
Thiazole carboxamide derivative 16 DMJQBVH Patented NA [8]
Thiazole carboxamide derivative 17 DMPMN92 Patented NA [8]
Thiazole carboxamide derivative 18 DM987MK Patented NA [8]
Thiazole carboxamide derivative 19 DMW59Q4 Patented NA [8]
Thiazole carboxamide derivative 2 DMLIRGM Patented NA [8]
Thiazole carboxamide derivative 20 DMORSH9 Patented NA [8]
Thiazole carboxamide derivative 21 DMTJBCG Patented NA [8]
Thiazole carboxamide derivative 22 DM6WTR2 Patented NA [8]
Thiazole carboxamide derivative 23 DMMO6JY Patented NA [8]
Thiazole carboxamide derivative 24 DMZ6YB0 Patented NA [8]
Thiazole carboxamide derivative 25 DMLRTFX Patented NA [8]
Thiazole carboxamide derivative 26 DM8DHZ4 Patented NA [8]
Thiazole carboxamide derivative 27 DMV30QO Patented NA [8]
Thiazole carboxamide derivative 28 DMGEIZV Patented NA [8]
Thiazole carboxamide derivative 29 DMCRVO5 Patented NA [8]
Thiazole carboxamide derivative 3 DMLRA3C Patented NA [8]
Thiazole carboxamide derivative 30 DMEOKCB Patented NA [8]
Thiazole carboxamide derivative 4 DMI3X14 Patented NA [8]
Thiazole carboxamide derivative 5 DM2H95E Patented NA [8]
Thiazole carboxamide derivative 6 DMWHCOE Patented NA [8]
Thiazole carboxamide derivative 7 DMLBK8V Patented NA [8]
Thiazole carboxamide derivative 8 DMVOTKN Patented NA [8]
Thiazole carboxamide derivative 9 DM5P04R Patented NA [8]
Thieno[3,2-c]pyridine-7-carboxamide derivative 1 DM1C8MA Patented Small molecular drug [8]
Thieno[3,2-c]pyridine-7-carboxamide derivative 2 DMOWFA5 Patented Small molecular drug [8]
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⏷ Show the Full List of 99 Drug(s)

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

References

1 Emerging drugs for the therapy of primary and post essential thrombocythemia, post polycythemia vera myelofibrosis. Expert Opin Emerg Drugs. 2009 Sep;14(3):471-9.
2 ClinicalTrials.gov (NCT03563326) Intraperitoneal Infusion of EpCAM CAR-T Cell in Advanced Gastric Cancer With Peritoneal Metastasis (WCH-GC-CART)
3 Clinical pipeline report, company report or official report of Etubics.
4 ClinicalTrials.gov (NCT01281592) A Study of LOR-253 HCl in Patients With Advanced or Metastatic Solid Tumours. U.S. National Institutes of Health.
5 ClinicalTrials.gov (NCT01139788) A Study of LY2624587 in Patients With Advanced Cancer. U.S. National Institutes of Health.
6 ClinicalTrials.gov (NCT01918930) Tissue Procurement Substudy for Participants in Study CP-MGA271-01. U.S. National Institutes of Health.
7 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
8 PDK1 disruptors and modulators: a patent review.Expert Opin Ther Pat. 2015 May;25(5):513-37.
9 Cathepsin B and L inhibitors: a patent review (2010 - present).Expert Opin Ther Pat. 2017 Jun;27(6):643-656.