Details of the Drug

General Information of Drug (ID: DM2TNJ1)

Drug Name

Molgramostim

Synonyms

Genfulin; Molgramostim (topical, wound healing); Molgramostim (topical, wound healing), GeneScience; GM-CSF (topical, woundhealing), GeneScience; Granulocyte-macrophage colony stimulating factor (topical, wound healing), GeneScience

Indication

Disease Entry	ICD 11	Status	REF
Autoimmune pulmonary alveolar proteinosis	CB04.31	Phase 3	[1]
Wound healing	EL8Y	Phase 1	[2]
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Cross-matching ID

DrugBank ID: DB12525
TTD ID: D0U0HX

Repurposed Drugs (RPD)

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Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
GMCSFR-alpha (CSF2RA)	TT6MP2Z	CSF2R_HUMAN	Agonist	[3]

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Molecular Interaction Atlas (MIA)

MIA Detail

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References

1	ClinicalTrials.gov (NCT04544293) Clinical Trial of Inhaled Molgramostim Nebulizer Solution in Autoimmune Pulmonary Alveolar Proteinosis (aPAP) (IMPALA-2). U.S. National Institutes of Health.
2	ClinicalTrials.gov (NCT02468908) Inhaled Molgramostim (rhGM-CSF) in Healthy Adult Subjects.
3	Clinical pipeline report, company report or official report of gensci-china.