General Information of Drug (ID: DM2UQ0R)

Drug Name
9-(2-Hydroxypropyl)-9H-adenine
Synonyms
9-(2-Hydroxypropyl)adenine; 1-(6-aminopurin-9-yl)propan-2-ol; CHEMBL504495; MJZYTEBKXLVLMY-UHFFFAOYSA-N; 9-(2-Hydroxypropyl)-9H-adenine; AC1L1CKL; 9H-Purine-9-ethanol, 6-amino-.alpha.-methyl-; SCHEMBL904363; CTK6A8458; 9-(2-Hydroxy-1-propyl)adenine; BCP14341; BDBM50257055; 3-(6-Amino-9-purinyl)-2-propanol; AKOS010941288; TRA0093894; AN-7936; 1-(6-Amino-purin-9-yl)-propan-2-ol; SY022843; A3032; 4CH-024207; 4CH-018216; 1-(6-Amino-9H-purin-9-yl)-2-propanol #; MFCD07369451 (97+%)
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 193.21
Logarithm of the Partition Coefficient (xlogp) -0.4
Rotatable Bond Count (rotbonds) 2
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C8H11N5O
IUPAC Name
1-(6-aminopurin-9-yl)propan-2-ol
Canonical SMILES
CC(CN1C=NC2=C(N=CN=C21)N)O
InChI
InChI=1S/C8H11N5O/c1-5(14)2-13-4-12-6-7(9)10-3-11-8(6)13/h3-5,14H,2H2,1H3,(H2,9,10,11)
InChIKey
MJZYTEBKXLVLMY-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
1942
TTD ID
D0Q6KO

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Adenosine A2a receptor (ADORA2A) TTM2AOE AA2AR_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 8-Bromo-9-alkyl adenine derivatives as tools for developing new adenosine A2A and A2B receptors ligands. Bioorg Med Chem. 2009 Apr 1;17(7):2812-22.