Details of the Drug

General Information of Drug (ID: DM2XTB9)

Drug Name	WAY-132983
Synonyms	WAY-132983
Drug Type	Small molecular drug
Structure
Structure	3D MOL	2D MOL
#Ro5 Violations (Lipinski): 0	Molecular Weight	343.9
	Logarithm of the Partition Coefficient	Not Available
	Rotatable Bond Count	8
	Hydrogen Bond Donor Count	1
	Hydrogen Bond Acceptor Count	5
Chemical Identifiers	Formula C16H26ClN3OS IUPAC Name (3R)-3-(3-hexylsulfanylpyrazin-2-yl)oxy-1-azabicyclo[2.2.1]heptane;hydrochloride Canonical SMILES CCCCCCSC1=NC=CN=C1O[C@H]2CN3CCC2C3.Cl InChI InChI=1S/C16H25N3OS.ClH/c1-2-3-4-5-10-21-16-15(17-7-8-18-16)20-14-12-19-9-6-13(14)11-19;/h7-8,13-14H,2-6,9-12H2,1H3;1H/t13?,14-;/m0./s1 InChIKey QAXRREHLPKHWBI-IJDFPQMLSA-N
Cross-matching ID	PubChem CID 45260374 TTD ID D0PZ9R

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Muscarinic acetylcholine receptor M1 (CHRM1)	TTZ9SOR	ACM1_HUMAN	Agonist	[1]

------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Muscarinic acetylcholine receptor M1 (CHRM1)	DTT	CHRM1	8.42E-02	-0.38	-0.24
Muscarinic acetylcholine receptor M1 (CHRM1)	DTT	CHRM1	2.55E-01	0.14	0.37

Molecular Expression Atlas (MEA)

Jump to Detail Molecular Expression Atlas of This Drug

References

1	Pharmacological comparison of muscarinic ligands: historical versus more recent muscarinic M1-preferring receptor agonists. Eur J Pharmacol. 2009 Mar 1;605(1-3):53-6.