Details of the Drug

General Information of Drug (ID: DM3M652)

• Drug Name: Daio-Orengedokuto (DOT)
• Synonyms: 26159-34-2; Miranax; Naproxen sodium salt; Synflex; Naprodol; Naprodil; Leniartril; Gibixen; Floxalin; Flogogin; Aprowell; Anapran; Primeral; Pactens; Naprovite; Gibinap; Floneks; Anaprotab; Monarit; Karoksen; Sodimax; Natrioxen; Floginex; Opraks; Kapnax; Tandax; Flogen; Nixal; Aprol; Naprux Gesic; Causalon Pro; Naproxen natrium; Axer Alfa; Dysmenalgit; Veradol; Naprium; Diocodal; Proxen; Prexan; Naprux; A-Nox; Xenar; Laser; Apo-Napro-NA; UNII-9TN87S3A3C; sodium na

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight; 252.24
  Logarithm of the Partition Coefficient; Not Available
  Rotatable Bond Count; 3
  Hydrogen Bond Donor Count; 0
  Hydrogen Bond Acceptor Count; 3
• Chemical Identifiers:
  Formula: C14H13NaO3
  IUPAC Name: sodium;(2S)-2-(6-methoxynaphthalen-2-yl)propanoate
  Canonical SMILES: C[C@@H](C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)[O-].[Na+]
  InChI: InChI=1S/C14H14O3.Na/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10;/h3-9H,1-2H3,(H,15,16);/q;+1/p-1/t9-;/m0./s1
  InChIKey: CDBRNDSHEYLDJV-FVGYRXGTSA-M
• Cross-matching ID:
  PubChem CID: 23681059
  ChEBI ID: CHEBI:7477
  CAS Number: 26159-34-2
  TTD ID: D09CGL

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Pancreatic triacylglycerol lipase (PNLIP)	TTXMY0J	LIPP_HUMAN	Inhibitor	[1]

References

• [1] Daio-Orengedokuto inhibits HMG-CoA reductase and pancreatic lipase. Biol Pharm Bull. 2002 Nov;25(11):1442-5.