Details of the Drug

General Information of Drug (ID: DM3PAS4)

Drug Name
Pyridobenzimidazole
Synonyms ZINC72190057; AKOS026719278; benzo[4,5]imidazo[1,2-a]pyridin-4-ylmethanol
Indication
Disease Entry ICD 11 Status REF
Fungal infection 1F29-1F2F Investigative [1]
Therapeutic Class
Antifungal Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 169.18
Logarithm of the Partition Coefficient (xlogp) 1.1
Rotatable Bond Count (rotbonds) 0
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 2
Chemical Identifiers
Formula
C10H7N3
IUPAC Name
6H-imidazo[4,5-f]quinoline
Canonical SMILES
C1=CNC2=CC=C3C(=NC=N3)C2=C1
InChI
InChI=1S/C10H7N3/c1-2-7-8(11-5-1)3-4-9-10(7)13-6-12-9/h1-6,11H
InChIKey
FOLSLCYDXFQZJP-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
164569
CAS Number
233-55-6
TTD ID
D0C9KY

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Fungal Papulacandin B resistance protein 1 (Fung FKS1) TTZMS1L FKS1_YEAST Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Novel antifungal agents, targets or therapeutic strategies for the treatment of invasive fungal diseases: a review of the literature (2005-2009). Rev Iberoam Micol. 2009 Mar 31;26(1):15-22.