Details of the Drug

General Information of Drug (ID: DM3PZXN)

Drug Name
Taliglucerase alfa
Synonyms Elelyso (TN)
Indication
Disease Entry ICD 11 Status REF
Metabolic disorder 5C50-5D2Z Approved [1]
ADMET Property
Clearance
The sytemic clearance of drug is 30 L/h []
Half-life
The concentration or amount of drug in body reduced by one-half in 18.9 - 28.7 minutes [2]
Vd
The volume of distribution (Vd) of drug is 7.30-11.7 L []
Cross-matching ID
DrugBank ID
DB08876
TTD ID
D0G6HA

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glucosylceramidase (GBA) TT1B5PU GLCM_HUMAN Modulator [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7444).
2 Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 1352 Drug Compounds
3 Nat Rev Drug Discov. 2013 Feb;12(2):87-90.