Details of the Drug

General Information of Drug (ID: DM64YJW)

Drug Name
Amitivir
Synonyms LY-217896
Indication
Disease Entry ICD 11 Status REF
Virus infection 1A24-1D9Z Terminated [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 126.14
Logarithm of the Partition Coefficient (xlogp) 0.7
Rotatable Bond Count (rotbonds) 1
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C3H2N4S
IUPAC Name
1,3,4-thiadiazol-2-ylcyanamide
Canonical SMILES
C1=NN=C(S1)NC#N
InChI
InChI=1S/C3H2N4S/c4-1-5-3-7-6-2-8-3/h2H,(H,5,7)
InChIKey
YUCHAYRHHXJNQK-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
65912
CAS Number
111393-84-1
TTD ID
D0U0FH

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Herpes simplex virus DNA polymerase UL30 (HSV UL30) TTIU7X1 DPOL_HHV11 Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001039)
2 Approaches and strategies for the treatment of influenza virus infections. Antivir Chem Chemother. 1999 Jul;10(4):155-85.