Details of the Drug

General Information of Drug (ID: DM71BFM)

Drug Name

DNA-Ad

Synonyms

DNA-prime/adenovirus (Ad5)-boost CSP-and AMA1-encoding malaria vaccine (Biojector2000, intramuscular), US NavalMedical Research Center (NMRC)/Bioject/Vical/GenVec

Indication

Disease Entry	ICD 11	Status	REF
Malaria	1F40-1F45	Phase 1/2	[1]
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Drug Type

Vaccine

Cross-matching ID

TTD ID: D03KHQ

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Plasmodium Apical membrane protein (Malaria AMA-1)	TTQZW34	AMA1_PLAFF	Not Available	[2]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT00870987) Clinical Trial for Malaria Vaccines to Test for Safety, Immune Response and Protection Against Malaria. U.S. National Institutes of Health.
2	Sterile immunity to malaria after DNA prime/adenovirus boost immunization is associated with effector memory CD8+T cells targeting AMA1 class I epitopes. PLoS One. 2014 Sep 11;9(9):e106241.