Details of the Drug

General Information of Drug (ID: DM7I2AC)

Drug Name

mRNA-3745

Indication

Disease Entry	ICD 11	Status	REF
Glycogen storage disease type IA	5C51.3	Phase 1	[1]
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Drug Type

mRNA therapy

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Glucose-6-phosphatase catalytic subunit 1 messenger RNA (G6PC1 mRNA)	TTL5KSF	G6PC1_HUMAN	Not Available	[2]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT05095727) A Phase 1/2, Adaptive, Open-label, Single Ascending Dose to Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of mRNA-3745 in Participants With Glycogen Storage Disease Type 1a (GSD1a), Followed by an Open-label Extension. U.S.National Institutes of Health.
2	Clinical pipeline report, company report or official report of Moderna