Details of the Drug

General Information of Drug (ID: DM7PGOJ)

Drug Name

GSK2556286

Synonyms

GSK2556286; UNII-J9U8H9VQV0; GSK-286; J9U8H9VQV0; GSK-2556286; 1210456-20-4; GSK286; 6-((4-(2,3-Dimethylphenoxy)-1-piperidinyl)methyl)-2,4(1H,3H)-pyrimidinedione; 2,4(1H,3H)-Pyrimidinedione, 6-((4-(2,3-dimethylphenoxy)-1-piperidinyl)methyl)-; 6-[[4-(2,3-dimethylphenoxy)piperidin-1-yl]methyl]-1H-pyrimidine-2,4-dione; CHEMBL4650308; SCHEMBL19380190; EX-A6180; MS-24944; HY-147017; CS-0514179; Z644646478

Indication

Disease Entry	ICD 11	Status	REF
Tuberculosis	1B10-1B14	Phase 1	[1]
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Drug Type

Small molecule

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C18H23N3O3
Canonical SMILES: CC1=C(C(=CC=C1)OC2CCN(CC2)CC3=CC(=O)NC(=O)N3)C
InChI: InChI=1S/C18H23N3O3/c1-12-4-3-5-16(13(12)2)24-15-6-8-21(9-7-15)11-14-10-17(22)20-18(23)19-14/h3-5,10,15H,6-9,11H2,1-2H3,(H2,19,20,22,23)
InChIKey: AZOFJHATIPDIER-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 45833762
TTD ID: D07XUC

References

1	ClinicalTrials.gov (NCT04472897) A Randomised, Double Blind (Sponsor Unblinded), Placebo-controlled, First Time in Human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Repeat Oral Doses and the Food Effect of GSK2556286 in Healthy Adult Participants. U.S.National Institutes of Health.