Details of the Drug

General Information of Drug (ID: DM7VJE1)

Drug Name

IONIS-TMPRSS6-LRx

Indication

Disease Entry	ICD 11	Status	REF
Beta thalassemia	3A50.2	Phase 2	[1]
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Drug Type

Antisense oligonucleotide

Sequence

CUUUATTCCAAAGGGCAGCU

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
TMPRSS6 messenger RNA (TMPRSS6 mRNA)	TTNIUKC	TMPS6_HUMAN	Inhibitor	[2]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT04059406) Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS TMPRSS6-LRx. U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of Ionis Pharmaceuticals.