Details of the Drug

General Information of Drug (ID: DM847I2)

• Drug Name: Imidazolyl urea derivative 1
• Synonyms: PMID26413912-Compound-56
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 291.77
  Logarithm of the Partition Coefficient (xlogp); 2.9
  Rotatable Bond Count (rotbonds); 5
  Hydrogen Bond Donor Count (hbonddonor); 0
  Hydrogen Bond Acceptor Count (hbondacc); 2
• Chemical Identifiers:
  Formula: C15H18ClN3O
  IUPAC Name: N-(4-chlorobutyl)-N-methyl-4-phenylimidazole-1-carboxamide
  Canonical SMILES: CN(CCCCCl)C(=O)N1C=C(N=C1)C2=CC=CC=C2
  InChI: InChI=1S/C15H18ClN3O/c1-18(10-6-5-9-16)15(20)19-11-14(17-12-19)13-7-3-2-4-8-13/h2-4,7-8,11-12H,5-6,9-10H2,1H3
  InChIKey: ULOIHJOBJLPNOI-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 44252357
  TTD ID: D09AAB

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Fatty acid amide hydrolase (FAAH)	TTDP1UC	NOUNIPROTAC	Inhibitor	[1]

Molecular Expression Atlas of This Drug

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Fatty acid amide hydrolase (FAAH)	DTT	NO-GeName	2.65E-01	0.02	0.1

References

• [1] Fatty acid amide hydrolase inhibitors: a patent review (2009-2014).Expert Opin Ther Pat. 2015;25(11):1247-66.