General Information of Drug (ID: DM92LH2)

Drug Name
Pentamycin
Synonyms
FemiFect; Pentamycin; LMV-602; Pentamycin vaginal tablets (vaginitis); Pentamycin, Necura; Pentamycin, Shogoo; Pruri-Ex; SPK-0602; N-Pent, Necura; N-Pent, Shogoo; Pentamycin vaginal tablets (vaginitis), Lumavita
Indication
Disease Entry ICD 11 Status REF
Vulvovaginitis GA02.0 Approved [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C35H58O12
Canonical SMILES
CCCCCC(C1C(CC(CC(CC(CC(CC(C(C(C(=CC=CC=CC=CC=CC(C(OC1=O)C)O)C)O)O)O)O)O)O)O)O)O
InChI
1S/C35H58O12/c1-4-5-11-16-29(41)32-30(42)20-26(38)18-24(36)17-25(37)19-27(39)21-31(43)34(45)33(44)22(2)14-12-9-7-6-8-10-13-15-28(40)23(3)47-35(32)46/h6-10,12-15,23-34,36-45H,4-5,11,16-21H2,1-3H3/b7-6+,10-8+,12-9+,15-13+,22-14+/t23-,24+,25-,26+,27-,28+,29-,30+,31-,32-,33-,34-/m1/s1
InChIKey
AGJUUQSLGVCRQA-SWOUQTJZSA-N
Cross-matching ID
PubChem CID
5282200
CAS Number
-98-6
TTD ID
D0A9ZX

Molecular Interaction Atlas of This Drug


Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Ribosomal 23S RNA methyltransferase Erm (erm) DEW6V07 A0A5N1AHF6_CORAY Substrate [2]
Ribosomal 23S RNA methyltransferase Erm (erm) DEA65D8 A0A381KDL2_CORJE Substrate [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Pipeline of Lumavita in clinical development of anti-infectives. 2007
2 High frequency of macrolide resistance mechanisms in clinical isolates of Corynebacterium species. Microb Drug Resist. 2010 Dec;16(4):273-7.