Details of the Drug

General Information of Drug (ID: DM9PK1R)

Drug Name

2,5-dichloro-N-phenylthiophene-3-sulfonamide

Synonyms

CHEMBL1171971; 2,5-dichloro-N-phenylthiophene-3-sulfonamide; SCHEMBL7579927; BDBM50321450

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski): 0

Molecular Weight (mw)

308.2

Logarithm of the Partition Coefficient (xlogp)

4

Rotatable Bond Count (rotbonds)

3

Hydrogen Bond Donor Count (hbonddonor)

1

Hydrogen Bond Acceptor Count (hbondacc)

4

Chemical Identifiers

Formula: C10H7Cl2NO2S2
IUPAC Name: 2,5-dichloro-N-phenylthiophene-3-sulfonamide
Canonical SMILES: C1=CC=C(C=C1)NS(=O)(=O)C2=C(SC(=C2)Cl)Cl
InChI: InChI=1S/C10H7Cl2NO2S2/c11-9-6-8(10(12)16-9)17(14,15)13-7-4-2-1-3-5-7/h1-6,13H
InChIKey: ILXABJHIVUDACG-UHFFFAOYSA-N

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Plasmodium CDK Pfmrk (Malaria Pfmrk)	TTSFWA7	P90584_PLAFA	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Activity of substituted thiophene sulfonamides against malarial and mammalian cyclin dependent protein kinases, Bioorg. Med. Chem. Lett. 20(13):3863-3867 (2010).