Details of the Drug

General Information of Drug (ID: DM9ZHE3)

Drug Name
PTC-AADC
Indication
Disease Entry ICD 11 Status REF
Aromatic L-amino acid decarboxylase deficiency 5C59.00 Phase 2 [1]
Drug Type
Gene therapy
Cross-matching ID
TTD ID
D4X6SZ

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Aromatic-L-amino-acid decarboxylase (DDC) TTN451K DDC_HUMAN Not Available [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Aromatic L-amino acid decarboxylase deficiency
ICD Disease Classification 5C59.00
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Aromatic-L-amino-acid decarboxylase (DDC) DTT DDC 7.84E-03 -1.49 -1.01
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT04903288) An Open-Label Trial to Address the Safety of the SmartFlow MR-Compatible Ventricular Cannula for Administering Eladocagene Exuparvovec to Pediatric Subjects. U.S.National Institutes of Health.