Details of the Drug

General Information of Drug (ID: DMA5T3J)

Drug Name

Pepticlere

Synonyms

DP-68; DP-74; Small peptide beta amyloid protein fibril formation inhibitors, Proteotech; Alzheimers disease therapy (nasal spray), ProteTech; Small peptide A-beta protein fibril formation inhibitors, Proteotech; Laminin alpha chain derivatives (Alzheimer's disease), Proteotech; 6-9 mer peptide analogs (Alzheimer's disease), Proteotech

Indication

Disease Entry	ICD 11	Status	REF
Alzheimer disease	8A20	Preclinical	[1]
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Cross-matching ID

TTD ID: D0G7LP

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Amyloid beta A4 protein (APP)	TTE4KHA	A4_HUMAN	Inhibitor	[2]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease

Alzheimer disease

ICD Disease Classification

8A20

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Amyloid beta A4 protein (APP)	DTT	APP	1.60E-02	-0.07	-0.31

Molecular Expression Atlas (MEA)

MEA Detail

Jump to Detail Molecular Expression Atlas of This Drug

References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800023984)
2	Preclinical trail of Pepticlere (DP-74) for treating Alzheimer's disease. ProteoTech Inc.