Details of the Drug

General Information of Drug (ID: DMARBF9)

• Drug Name: Benzaldehyde O-4-propoxyphenylcarbamoyl oxime
• Synonyms: CHEMBL592635; benzaldehyde O-4-propoxyphenylcarbamoyl oxime

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 298.34
  Logarithm of the Partition Coefficient (xlogp); 4
  Rotatable Bond Count (rotbonds); 7
  Hydrogen Bond Donor Count (hbonddonor); 1
  Hydrogen Bond Acceptor Count (hbondacc); 4
• Chemical Identifiers:
  Formula: C17H18N2O3
  IUPAC Name: [(E)-benzylideneamino] N-(4-propoxyphenyl)carbamate
  Canonical SMILES: CCCOC1=CC=C(C=C1)NC(=O)O/N=C/C2=CC=CC=C2
  InChI: InChI=1S/C17H18N2O3/c1-2-12-21-16-10-8-15(9-11-16)19-17(20)22-18-13-14-6-4-3-5-7-14/h3-11,13H,2,12H2,1H3,(H,19,20)/b18-13+
  InChIKey: AIEVCSUZILYYSA-QGOAFFKASA-N
• Cross-matching ID:
  PubChem CID: 20872805
  TTD ID: D0Z5QM

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Fatty acid amide hydrolase (FAAH)	TTDP1UC	NOUNIPROTAC	Inhibitor	[1]

Molecular Expression Atlas of This Drug

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Fatty acid amide hydrolase (FAAH)	DTT	NO-GeName	2.65E-01	0.02	0.1

References

• [1] Oxime carbamate--discovery of a series of novel FAAH inhibitors. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1272-7.