Details of the Drug

General Information of Drug (ID: DMBPJ9U)

Drug Name

PEGylated pitrakinra

Synonyms

Aeroderm; Dermalast; AER-003; PEGylated pitrakinra (subcutaneous, eczema/allergy), Aerovance; PEGylated AER-001 (subcutaneous, eczema/allergy), Aerovance; PEGylated IL-4 variant (subcutaneous, eczema/allergy), Aerovance

Indication

Disease Entry	ICD 11	Status	REF
Asthma	CA23	Phase 2	[1]
Allergy	4A80-4A85	Investigative	[2]
------------------------------------------------------------------------------------

Drug Type

Monoclonal antibody

Cross-matching ID

TTD ID: D00KQN

Repurposed Drugs (RPD)

Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Interleukin-13 (IL13)	TT0GVCH	IL13_HUMAN	Modulator	[2]
Interleukin-4 (IL4)	TTLGTKB	IL4_HUMAN	Modulator	[2]

------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT00801853) A Study of the Treatment-Sparing Effects of AEROVANT AER 001 Inhalation Powder in Asthma Patients, AEROTRIAL
2	The potential of biologics for the treatment of asthma. Nat Rev Drug Discov. 2012 Dec;11(12):958-72.