Details of Disease

General Information of Disease (ID: DISW9QNS)

• Disease Name: Asthma
• Synonyms: exercise induced asthma; exercise-induced asthma; chronic obstructive asthma with status asthmaticus; chronic obstructive asthma; chronic obstructive asthma with acute exacerbation; bronchial hyperreactivity
• Disease Class: CA23: Asthma
• Definition: A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors resulting in recurring periods of wheezing (a whistling sound while breathing), chest tightness, shortness of breath, mucus production and coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, exercise, stress, reflux disease, medications, foods and emotional anxiety.
• Disease Hierarchy:
  DISCZT2B: Bronchial disorder
  DISW9QNS: Asthma
• ICD Code:
  ICD-11: ICD-11: CA23
  ICD-10: ICD-10: J45, J45.8
  ICD-9: ICD-9: 493
  Expand ICD-11: 'CA23
  Expand ICD-10: 'J45; 'J45.8
  Expand ICD-9: 493
• Disease Identifiers:
  MONDO ID: MONDO_0004979
  MESH ID: D001249
  UMLS CUI: C0004096
  MedGen ID: 2109
  HPO ID: HP:0002099
  SNOMED CT ID: 195967001

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 77 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Aminophylline	DML2NIB	Approved	Small molecular drug	[1]
Arformoterol	DMYM974	Approved	Small molecular drug	[2]
Bambuterol	DMKLSHF	Approved	Small molecular drug	[3]
Beclomethasone	DMZPHIK	Approved	Small molecular drug	[4]
Benralizumab	DM7P1J4	Approved	Monoclonal antibody	[5]
Betamethasone	DMAHJEF	Approved	Small molecular drug	[6]
Bitolterol	DMK6XAV	Approved	Small molecular drug	[7]
Brodalumab	DMASDQ6	Approved	Monoclonal antibody	[8]
Budesonide	DMJIBAW	Approved	Small molecular drug	[9]
Chymotrypsin	DM51HQ0	Approved	NA	[7]
Ciclesonide	DM2NA4K	Approved	Small molecular drug	[10]
Cinalukast	DMFIC0M	Approved	Small molecular drug	[11]
CNTO-1959	DMPC2QY	Approved	Antibody	[12]
Colforsin daropate hci	DMJ01D8	Approved	Small molecular drug	[13]
Cortisone Acetate	DMG8K57	Approved	Small molecular drug	[14]
Cromoglicate	DM74LZK	Approved	Small molecular drug	[15]
Desonide	DMTP2NJ	Approved	Small molecular drug	[16]
Dexamethasone	DMMWZET	Approved	Small molecular drug	[17]
Doxofylline	DMEDKZH	Approved	Small molecular drug	[7]
Dupilumab	DMOAD2Y	Approved	Antibody	[18]
Dyphylline	DM8DZC1	Approved	Small molecular drug	[19]
Enprofylline	DMFYZKN	Approved	Small molecular drug	[20]
Ephedrine	DMMV0KW	Approved	Small molecular drug	[21]
Epinephrine	DM3KJBC	Approved	Small molecular drug	[22]
Fenoterol	DMIP3ZV	Approved	Small molecular drug	[23]
Flunisolide	DMZSWQC	Approved	Small molecular drug	[24]
Fluprednisolone	DMZWBKG	Approved	Small molecular drug	[7]
Formoterol	DMSOURV	Approved	Small molecular drug	[25]
GW642444	DMV4KOA	Approved	Small molecular drug	[26]
GW685698X	DML72VJ	Approved	Small molecular drug	[27]
Hydriodic acid iodine-125	DMWI8CR	Approved	Small molecular drug	[7]
Hydrocortisone	DMGEMB7	Approved	Small molecular drug	[28]
Ibudilast	DM4LSPN	Approved	Small molecular drug	[29]
Indacaterol	DMQJHR7	Approved	Small molecular drug	[30]
Infliximab	DMH7OIA	Approved	Antibody	[31]
Iodinated glycerol	DMWNO8S	Approved	Small molecular drug	[7]
Isoetharine	DMITSEH	Approved	Small molecular drug	[32]
Khellin	DMNU65W	Approved	Small molecular drug	[7]
Krypton, Kr-81m	DM7XOHB	Approved	Small molecular drug	[7]
Levalbuterol	DM5YBO1	Approved	Small molecular drug	[7]
Lodoxamide	DMTY2K8	Approved	Small molecular drug	[7]
Mepolizumab	DMW2GEJ	Approved	Monoclonal antibody	[33]
Metaproterenol Sulfate	DMTQS9A	Approved	Small molecular drug	[34]
Methacholine Chloride	DMGS4QH	Approved	Small molecular drug	[35]
Methylprednisolone	DM4BDON	Approved	Small molecular drug	[36]
Mometasone	DM45OJN	Approved	Small molecular drug	[37]
Montelukast	DMD157S	Approved	Small molecular drug	[38]
Norepinephrine	DMOUC09	Approved	Small molecular drug	[39]
Omalizumab	DMETVFJ	Approved	Monoclonal antibody	[40]
Oxitropium bromide	DM9FKSR	Approved	Small molecular drug	[7]
Pemirolast	DML97WV	Approved	Small molecular drug	[41]
Pirbuterol	DMI5678	Approved	Small molecular drug	[42]
Pranlukast	DMYHDCA	Approved	Small molecular drug	[43]
Prednisolone	DMQ8FR2	Approved	Small molecular drug	[44]
Prednisone	DM2HG4X	Approved	Small molecular drug	[45]
Procaterol	DM1M0Q4	Approved	Small molecular drug	[46]
Protokylol Hydrochloride	DMAHZKR	Approved	Small molecular drug	[7]
Repirinast	DM6KI0D	Approved	Small molecular drug	[7]
Reslizumab	DM0AUCH	Approved	Monoclonal antibody	[47]
Rimiterol	DMA47C6	Approved	Small molecular drug	[7]
Ritlecitinib	DMYKNME	Approved	NA	[48]
Roflumilast	DMPGHY8	Approved	Small molecular drug	[49]
Terbutaline	DMD4381	Approved	Small molecular drug	[50]
Theobromine	DMM8D3F	Approved	Small molecular drug	[7]
Theophylline	DMRJFN9	Approved	Small molecular drug	[51]
Tiotropium	DMFDC0Q	Approved	Small molecular drug	[52]
Tralokinumab	DM6ENSJ	Approved	Monoclonal antibody	[53]
Tranilast	DME5Y64	Approved	Small molecular drug	[54]
Triamcinolone	DM98IXF	Approved	Small molecular drug	[55]
Vilanterol	DMF5EK1	Approved	Small molecular drug	[56]
VR315	DMLH3EW	Approved	NA	[7]
VR506	DMVJQC1	Approved	NA	[7]
VR632	DMI1J0T	Approved	NA	[7]
Ximelegatran	DMU8ANS	Approved	Small molecular drug	[57]
Zafirlukast	DMHNQOG	Approved	Small molecular drug	[58]
Zileuton	DMVRIC2	Approved	Small molecular drug	[59]
Beclomethasone dipropionate	DM5NW1E	Phase 4	NA	[60]

This Disease is Treated as An Indication in 163 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
RELVARTM or BREOTM ELLIPTATM	DMCW7ZL	NDA filed	NA	[61]
A378	DMUWRTB	IND submitted	Monoclonal antibody	[62]
ABT-761	DM3FIC2	Phase 3	Small molecular drug	[63]
AMG 386	DMQJXL4	Phase 3	Small molecular drug	[64]
Astegolimab	DMKOHC5	Phase 3	Monoclonal antibody	[65]
Bavituximab	DMCGW5R	Phase 3	Monoclonal antibody	[66]
CBP-201	DMWYNN1	Phase 3	Antibody	[67]
D-5519	DM9FAJM	Phase 3	NA	[68]
Depemokimab	DMG9VHN	Phase 3	Monoclonal antibody	[69]
E004	DML36CH	Phase 3	NA	[70]
Fevipiprant	DM4NX0C	Phase 3	Small molecular drug	[71]
GMI-1070	DMJ432G	Phase 3	Small molecular drug	[72]
GSK3511294	DMWKSFY	Phase 3	Monoclonal antibody	[73]
ISRAPAFANT	DMP61YB	Phase 3	Small molecular drug	[74]
MDI-P	DM2C4ZC	Phase 3	Small molecular drug	[75]
Pumactant	DM35MM1	Phase 3	NA	[76]
QAW-039	DMPCFXN	Phase 3	NA	[77]
Quinotolast	DMDCQW0	Phase 3	Small molecular drug	[78]
SAR231893	DMHFBOG	Phase 3	NA	[79]
SAR440340	DMKYXSS	Phase 3	Antibody	[80]
Setipiprant	DMZ61IA	Phase 3	Small molecular drug	[81]
SOTB07	DMIG4OX	Phase 3	NA	[82]
VR647	DMMZC7J	Phase 3	NA	[83]
CEP1347	DMXCD69	Phase 2/3	Small molecular drug	[84]
Darbufelone	DMYVKM5	Phase 2/3	Small molecular drug	[85]
Aerovant	DMUB8WN	Phase 2a	NA	[86]
Bimosiamose	DM0TH9A	Phase 2a	Small molecular drug	[86]
ABT-308	DM6WN2D	Phase 2	NA	[87]
AHCQ	DMTV4HB	Phase 2	NA	[88]
AIM-102	DM8Y210	Phase 2	NA	[89]
Altrakincept	DMLSK01	Phase 2	Monoclonal antibody	[90]
AMG 157	DMMYB77	Phase 2	NA	[91]
AMG 853	DM973N4	Phase 2	Small molecular drug	[92]
Amlitelimab	DMKR3BQ	Phase 2	Antibody	[93]
Anrukinzumab	DMTG2O0	Phase 2	Monoclonal antibody	[94]
Anti-IL-5 Receptor mab	DMPRXU4	Phase 2	Monoclonal antibody	[95]
Anti-M1 prime	DMQFU1R	Phase 2	Antibody	[96]
AP-761	DMISQOZ	Phase 2	Small molecular drug	[97]
ASM-024	DM35S2I	Phase 2	NA	[98]
AZD-3199	DME8Z5M	Phase 2	NA	[99]
AZD-5069	DM3JSFK	Phase 2	NA	[100]
AZD1402	DM73O6I	Phase 2	NA	[101]
AZD8154	DMK13L1	Phase 2	Small molecule	[102]
AZX-100	DME0JMV	Phase 2	NA	[103]
BAY-X-7195	DM2XE80	Phase 2	Small molecular drug	[104]
BI-144807	DMWHWY2	Phase 2	NA	[105]
BI-54903	DM6D1G6	Phase 2	NA	[106]
BIO-1211	DMKICA3	Phase 2	Small molecular drug	[107]
BT-061	DM2LZIY	Phase 2	Antibody	[108]
CROMOGLYCATE LISETIL HYDROCHLORIDE	DM129T7	Phase 2	Small molecular drug	[109]
CSJ117	DMZJUV6	Phase 2	Antibody	[110]
CTP-543	DM3SYOK	Phase 2	NA	[111]
CYT003	DM4LJH8	Phase 2	NA	[112]
E-6700	DMUWJI4	Phase 2	NA	[113]
ETX-9101	DMZOA2L	Phase 2	NA	[114]
Flezelastine	DMCN4H6	Phase 2	Small molecular drug	[115]
Gallopamil	DMXBR27	Phase 2	Small molecular drug	[116]
GB001	DM58TGA	Phase 2	Small molecule	[117]
GPD-1116	DMOQ7YI	Phase 2	NA	[118]
GSK2245035	DMBWPZJ	Phase 2	Small molecular drug	[119]
GSK2269557	DMIN0SV	Phase 2	NA	[120]
GSK3772847	DM7J41B	Phase 2	Antibody	[121]
GSK679586	DM1527K	Phase 2	NA	[122]
GW-870086-X	DM489FT	Phase 2	NA	[123]
GW274150	DMZMCB1	Phase 2	Small molecular drug	[124]
HI-1640V	DMIUNJU	Phase 2	NA	[125]
IPL-512602	DMDEFXN	Phase 2	NA	[126]
Iralukast	DMQ3RWN	Phase 2	Small molecular drug	[127]
JNJ-39758979	DMD2O00	Phase 2	NA	[128]
JNJ-40929837	DMFB7LF	Phase 2	NA	[129]
KP-496	DMCO8UZ	Phase 2	NA	[130]
LCB-2183	DMY4IWC	Phase 2	NA	[131]
LEO 124249	DM7W0JE	Phase 2	NA	[48]
LM-1507.NA	DMW6VA0	Phase 2	NA	[132]
Masilukast	DMDTI0L	Phase 2	Small molecular drug	[133]
MEDI-528	DMDYVN8	Phase 2	Monoclonal antibody	[134]
MEDI9929	DMGD1YP	Phase 2	NA	[91]
MEMP1972A	DMUMCWS	Phase 2	NA	[135]
MK-1029	DM8ZTW7	Phase 2	NA	[136]
MTPS9579A	DMBFMT3	Phase 2	Antibody	[137]
N6022	DMN7EUO	Phase 2	Small molecular drug	[138]
Noberastine	DME8IFQ	Phase 2	Small molecular drug	[139]
Oglemilast	DMVC90W	Phase 2	Small molecular drug	[140]
ONO-6950	DMULDGG	Phase 2	NA	[141]
ONO-AE1-437	DMCUGI8	Phase 2	Small molecular drug	[142]
Ontazolast	DMS8Q7A	Phase 2	Small molecular drug	[143]
OX-914	DM5Q9RY	Phase 2	NA	[144]
Pascolizumab	DMU3XJP	Phase 2	Monoclonal antibody	[145]
PEGylated pitrakinra	DMBPJ9U	Phase 2	Monoclonal antibody	[146]
PF-06700841	DMMGSFV	Phase 2	NA	[48]
PF-3893787	DMC2FAL	Phase 2	Small molecular drug	[147]
PF-4191834	DM3DWKN	Phase 2	Small molecular drug	[148]
PIRODOMAST	DMC3T2S	Phase 2	Small molecular drug	[149]
PL-3994	DMHUCQS	Phase 2	NA	[150]
PNU-142731A	DMM8IAQ	Phase 2	NA	[151]
PRO-98498	DMJRBU4	Phase 2	NA	[152]
QBX258	DMTNQ5M	Phase 2	NA	[153]
R411	DMP7J0S	Phase 2	Small molecular drug	[154]
Rambazole	DMP2DNS	Phase 2	Small molecular drug	[155]
Revamilast	DM1FS2W	Phase 2	Small molecular drug	[156]
RG6341	DMPVJD1	Phase 2	NA	[157]
RNS-60	DMDNRU1	Phase 2	NA	[158]
RPT193	DMZJ0N3	Phase 2	Small molecule	[159]
RV-568	DM652CM	Phase 2	NA	[160]
SB-265610	DM8TKG5	Phase 2	Small molecular drug	[161]
SelK2	DMM6B6E	Phase 2	Antibody	[162]
SR-2640	DMFDA4Y	Phase 2	Small molecular drug	[163]
TA-270	DMZ7I51	Phase 2	NA	[164]
TC-6987	DMNFP21	Phase 2	NA	[165]
TD-8236	DMTOMJN	Phase 2	NA	[166]
Tepoxalin	DMVS61L	Phase 2	Small molecular drug	[167]
THR-18	DMBO021	Phase 2	NA	[168]
Tipelukast	DMS9BDQ	Phase 2	Small molecular drug	[169]
TJ-9	DMV68FN	Phase 2	NA	[170]
TPI ASM8	DMAWLVB	Phase 2	Antisense drug	[171]
VALERGEN-BT	DMOGFMK	Phase 2	NA	[172]
VALERGEN-DP	DM94QSZ	Phase 2	NA	[173]
WIN-901	DMQHSVY	Phase 2	NA	[174]
WY-50295-tromethamine	DMFVNSB	Phase 2	Small molecular drug	[175]
ZY-15106	DMYI1HV	Phase 2	Small molecular drug	[176]
MRx-4DP0004	DMXNPVE	Phase 1/2	Live biotherapeutic	[177]
Sodium pyruvate	DMST6A3	Phase 1/2	Small molecular drug	[178]
ADL 018	DMZDR43	Phase 1	Antibody	[179]
AI-128	DMC1C1Q	Phase 1	NA	[180]
AM-211	DMVXRYC	Phase 1	Small molecular drug	[181]
AMG 104	DM3XC31	Phase 1	Monoclonal antibody	[182]
AMG 282	DM92YWD	Phase 1	Antibody	[183]
ARO-MUC5AC	DM4AX65	Phase 1	RNA interference	[184]
ARO-RAGE	DMQI1EW	Phase 1	RNA interference	[185]
AZD0449	DMGB1PL	Phase 1	NA	[186]
AZD1419	DM6UOXF	Phase 1	NA	[187]
AZD4604	DMP3CSV	Phase 1	Small molecule	[188]
AZD8630	DMMUF0O	Phase 1	NA	[189]
BI 443651	DMVKL5J	Phase 1	NA	[190]
BI 894416	DMJ8EAJ	Phase 1	Small molecule	[191]
BM-212	DMIRX3Z	Phase 1	Small molecular drug	[192]
CI-959	DM6SCUK	Phase 1	Small molecular drug	[193]
CNT0-3157	DMIXI3U	Phase 1	NA	[194]
CNTO-3157	DMDQQUN	Phase 1	NA	[194]
CSL311	DMC21G0	Phase 1	Antibody	[195]
CVT-6883	DMY84TW	Phase 1	Small molecular drug	[196]
FP-025	DMH1NXO	Phase 1	NA	[197]
GDC-0214	DMCNSII	Phase 1	Small molecule	[198]
GRC-6211	DMZ0D3V	Phase 1	Small molecular drug	[199]
GSK-2239633	DMUNVXR	Phase 1	NA	[200]
GSK1440115	DMEJMTR	Phase 1	Small molecular drug	[201]
GSK2292767	DMIX891	Phase 1	Small molecule	[202]
IMA-026	DMTR257	Phase 1	NA	[203]
INO-4885	DMX1BRO	Phase 1	NA	[204]
Laevo-Bambuterol	DMC0VJF	Phase 1	NA	[205]
MEDI4212	DMBI4EN	Phase 1	NA	[206]
OPK-0018	DMLUYAJ	Phase 1	NA	[207]
PF-06413367	DMIOXEM	Phase 1	NA	[208]
PF-06444752	DM9UZTO	Phase 1	NA	[209]
RO-5271983	DMG7A3V	Phase 1	NA	[210]
RX-10001	DMQZ3T4	Phase 1	NA	[211]
SAR-21609	DMO8QY1	Phase 1	NA	[212]
SAR443765	DMLYI4Z	Phase 1	Nanobody	[213]
SB-436811	DMLPB0X	Phase 1	Small molecular drug	[214]
SDZ-MKS-492	DML6QJN	Phase 1	Small molecular drug	[215]
UPB-101	DMO1FVF	Phase 1	Antibody	[216]
VALERGEN-DS	DMH64ZW	Phase 1	NA	[173]
Xmab-7195	DME7IVL	Phase 1	NA	[217]

This Disease is Treated as An Indication in 164 Discontinued Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Clinprost	DM6E5VA	Discontinued in Preregistration	Small molecular drug	[218]
Ablukast	DMNKZ61	Discontinued in Phase 3	Small molecular drug	[219]
Ataprost	DMPTG39	Discontinued in Phase 3	Small molecular drug	[220]
BN 50730	DMZK70E	Discontinued in Phase 3	Small molecular drug	[221]
Broxaterol	DMRA6H5	Discontinued in Phase 3	Small molecular drug	[222]
DG031	DMO3AJS	Discontinued in Phase 3	Small molecular drug	[223]
FOROPAFANT	DML1DGP	Discontinued in Phase 3	Small molecular drug	[224]
Fosfructose	DM05XSZ	Discontinued in Phase 3	NA	[225]
Lenercept	DMN9KJ2	Discontinued in Phase 3	NA	[226]
ACREOZAST	DM5R3VR	Discontinued in Phase 2	Small molecular drug	[227]
APC-366	DM02DNQ	Discontinued in Phase 2	Small molecular drug	[228]
AR-D-111421	DMML5WB	Discontinued in Phase 2	NA	[229]
AS-35	DMC2WI7	Discontinued in Phase 2	Small molecular drug	[230]
AVAC	DMHLR34	Discontinued in Phase 2	NA	[231]
AZD-3778	DM4K085	Discontinued in Phase 2	Small molecular drug	[232]
Bamaquimast	DM8XXSV	Discontinued in Phase 2	Small molecular drug	[233]
BUTIXOCORT	DMD3LGL	Discontinued in Phase 2	Small molecular drug	[234]
CGRP	DMCRPKS	Discontinued in Phase 2	Small molecular drug	[235]
CI-1018	DM03XVA	Discontinued in Phase 2	Small molecular drug	[236]
CI-949	DMN4QSW	Discontinued in Phase 2	Small molecular drug	[237]
CJ-13610	DM1CDNS	Discontinued in Phase 2	Small molecular drug	[238]
Corus 1030	DMRVJ1A	Discontinued in Phase 2	NA	[239]
DS-4574	DM8GZWC	Discontinued in Phase 2	Small molecular drug	[240]
E-6080	DM296V7	Discontinued in Phase 2	Small molecular drug	[241]
E-6123	DMUW6QX	Discontinued in Phase 2	Small molecular drug	[242]
EPI-2010	DMJ52FZ	Discontinued in Phase 2	Antisense drug	[243]
FK-011	DMCINOE	Discontinued in Phase 2	NA	[244]
FK-224	DM1JUS0	Discontinued in Phase 2	Small molecular drug	[245]
FK-613	DMVASRY	Discontinued in Phase 2	NA	[246]
GSK159802	DM8J2AV	Discontinued in Phase 2	NA	[247]
GSK2190914	DMHZQ0T	Discontinued in Phase 2	NA	[248]
GSK2190915	DM89AV2	Discontinued in Phase 2	Small molecular drug	[249]
GSK256066	DMBYQJH	Discontinued in Phase 2	Small molecular drug	[250]
GSK870086	DM8J30W	Discontinued in Phase 2	NA	[251]
GW-766994	DMKC0J5	Discontinued in Phase 2	Small molecular drug	[252]
Imitrodast	DMQ2ULV	Discontinued in Phase 2	Small molecular drug	[253]
Isbufylline	DMWJ4TQ	Discontinued in Phase 2	Small molecular drug	[254]
IVL745	DMS5HX0	Discontinued in Phase 2	NA	[255]
KW-4490	DMSWDKX	Discontinued in Phase 2	NA	[256]
LTB 019	DM6G0PN	Discontinued in Phase 2	Small molecular drug	[257]
LY-223982	DMWB7DO	Discontinued in Phase 2	Small molecular drug	[258]
Mequitamium iodide	DM2DK4A	Discontinued in Phase 2	Small molecular drug	[259]
Milveterol	DMF1IH5	Discontinued in Phase 2	Small molecular drug	[260]
MK-591	DMVXTZG	Discontinued in Phase 2	Small molecular drug	[261]
MK-886	DMT0O7H	Discontinued in Phase 2	Small molecular drug	[262]
Nafagrel	DMKF3TD	Discontinued in Phase 2	Small molecular drug	[263]
Nolpitantium besilate	DMK5WLZ	Discontinued in Phase 2	Small molecular drug	[264]
Picumeterol	DMA13WI	Discontinued in Phase 2	Small molecular drug	[265]
Pumafentrine	DMI8T41	Discontinued in Phase 2	Small molecular drug	[266]
R-343	DMEJNM1	Discontinued in Phase 2	Small molecular drug	[267]
RPR-106541	DMRGC5B	Discontinued in Phase 2	NA	[268]
SC-45662	DMQ0T6L	Discontinued in Phase 2	Small molecular drug	[269]
SK&F-S-106203	DM2BDAW	Discontinued in Phase 2	NA	[270]
SRP 299	DMCK19W	Discontinued in Phase 2	NA	[271]
Sulukast	DMBSLZV	Discontinued in Phase 2	Small molecular drug	[272]
Tetrazolast meglumine	DMORMM8	Discontinued in Phase 2	Small molecular drug	[273]
TIBENELAST	DMYH2PU	Discontinued in Phase 2	Small molecular drug	[274]
V-11294A	DMEV1H5	Discontinued in Phase 2	NA	[275]
Valategrast	DM9AKDK	Discontinued in Phase 2	NA	[255]
WAY-123641	DMPE5XM	Discontinued in Phase 2	NA	[276]
ZD-2138	DMVFCX7	Discontinued in Phase 2	Small molecular drug	[277]
AVE-5883	DM3P84V	Discontinued in Phase 1/2	NA	[278]
NCX 950	DMNXCFZ	Discontinued in Phase 1/2	NA	[279]
Vepalimomab	DMG6O3X	Discontinued in Phase 1/2	Monoclonal antibody	[280]
ABN-912	DMADKHB	Discontinued in Phase 1	Antibody	[281]
ABT-080	DMTYWE9	Discontinued in Phase 1	NA	[282]
AMG 317	DMUO3T2	Discontinued in Phase 1	NA	[283]
AZD-1744	DMCOMG5	Discontinued in Phase 1	NA	[284]
BM-113	DMNE5SA	Discontinued in Phase 1	Small molecular drug	[285]
CGP-13774	DM8K8PZ	Discontinued in Phase 1	NA	[286]
F-11105	DMLRF7U	Discontinued in Phase 1	NA	[287]
GR-63799X	DM13GK8	Discontinued in Phase 1	Small molecular drug	[288]
GW-250495	DMWJZAP	Discontinued in Phase 1	NA	[289]
HSR-6071	DMCS06R	Discontinued in Phase 1	Small molecular drug	[290]
IPLl576092	DMCKJJH	Discontinued in Phase 1	NA	[291]
NIP-520	DMMT7BC	Discontinued in Phase 1	NA	[292]
NZ-107	DMXJO5F	Discontinued in Phase 1	Small molecular drug	[293]
PF-05212372	DMD83VY	Discontinued in Phase 1	NA	[294]
PF-3526299	DMMU1W3	Discontinued in Phase 1	NA	[295]
RG-7152	DMG9U8D	Discontinued in Phase 1	Small molecular drug	[296]
RG-7185	DM12VHC	Discontinued in Phase 1	NA	[297]
RO7040547	DMP0YNU	Discontinued in Phase 1	Antibody	[298]
RWJ-56423	DM6BIHE	Discontinued in Phase 1	Small molecular drug	[299]
SB-281832	DMYTAJW	Discontinued in Phase 1	NA	[300]
SDZ-PCO-400	DMZHOYM	Discontinued in Phase 1	Small molecular drug	[301]
SMP-028	DMQSGOD	Discontinued in Phase 1	NA	[302]
TR-14531	DMH5SA6	Discontinued in Phase 1	NA	[303]
YM-976	DMCDK6S	Discontinued in Phase 1	Small molecular drug	[304]
443C81	DMQ4X7Y	Terminated	NA	[309]
A-78773	DM4HRXI	Terminated	Small molecular drug	[310]
A-79175	DMT5ZFG	Terminated	Small molecular drug	[311]
AVE0675	DM4UTXV	Terminated	NA	[312]
AZD-2098	DM1P6TA	Terminated	NA	[313]
BABIM	DM8AGOE	Terminated	Small molecular drug	[314]
BAY-17-1998	DM7LZFQ	Terminated	NA	[315]
BAY-44-3428	DM40ORU	Terminated	NA	[316]
BI-L-357	DMBR48G	Terminated	Small molecular drug	[317]
BU-4601A	DM4OT0S	Terminated	Small molecular drug	[318]
BW B70C	DMTYCJ6	Terminated	Small molecular drug	[319]
CGS-13080	DMUPKYO	Terminated	Small molecular drug	[320]
CP-0597	DMS23JX	Terminated	NA	[321]
CV 6209	DMQBULC	Terminated	Small molecular drug	[322]
EFIPLADIB	DMJ0A5U	Terminated	Small molecular drug	[323]
EP-012637	DM4AEK3	Terminated	NA	[324]
Epocarbazolin-A	DMWRSXK	Terminated	Small molecular drug	[325]
Fenspiride hydrochloride	DMSQX57	Terminated	Small molecular drug	[326]
FK-355	DMIGXQF	Terminated	NA	[327]
FPL-55712	DMF1CDK	Terminated	Small molecular drug	[328]
FR-113680	DMCAZPR	Terminated	Small molecular drug	[329]
GCC-AP0341	DM8ZHN3	Terminated	Small molecular drug	[330]
GW-3600	DMSZH0I	Terminated	NA	[331]
ICI-198615	DM0195G	Terminated	Small molecular drug	[332]
Isomazole	DM4YJ2W	Terminated	Small molecular drug	[333]
KA-398	DM0MXWC	Terminated	NA	[334]
KC-11404	DM3H90W	Terminated	NA	[335]
KC-11425	DMC295V	Terminated	NA	[336]
KF-15570	DMUXJLQ	Terminated	Small molecular drug	[337]
KF-17625	DM7QEQJ	Terminated	Small molecular drug	[338]
L-648051	DMTKCNJ	Terminated	Small molecular drug	[339]
L-670596	DMW2SEV	Terminated	Small molecular drug	[340]
L-745337	DMOQIWH	Terminated	Small molecular drug	[341]
LF-801	DMTOSR7	Terminated	NA	[342]
LM-1376	DMF9XU4	Terminated	NA	[343]
LY-210073	DMUEB4P	Terminated	Small molecular drug	[344]
LY-255283	DMFIR0S	Terminated	Small molecular drug	[345]
LY-290154	DMPZ7AO	Terminated	NA	[346]
MCI-826	DMXLCB6	Terminated	Small molecular drug	[347]
MDL-43291	DMBIDQX	Terminated	Small molecular drug	[348]
MEN-10627	DM35ABD	Terminated	Small molecular drug	[349]
MEN-11149	DMEYNB0	Terminated	NA	[350]
Midaglizole	DM96WKA	Terminated	Small molecular drug	[351]
MOL-218	DM543VY	Terminated	NA	[352]
MX2/120	DMF62PU	Terminated	Small molecular drug	[353]
NPC-17731	DMGVIZY	Terminated	Small molecular drug	[354]
NS-1619	DMES0OT	Terminated	Small molecular drug	[355]
ON-579	DMTS6HB	Terminated	Small molecular drug	[356]
Org-9935	DMRZCH4	Terminated	Small molecular drug	[357]
OT-4003	DM9YOMX	Terminated	NA	[358]
PLR-8	DMG0MS3	Terminated	NA	[359]
R zileuton	DMA187T	Terminated	NA	[360]
RG-14893	DMKFQC7	Terminated	Small molecular drug	[361]
Ro 20-1724	DM0PSCF	Terminated	Small molecular drug	[362]
RP-58802B	DMQZ2JA	Terminated	Small molecular drug	[363]
RP-66153	DMX4E75	Terminated	Small molecular drug	[364]
SC-53228	DMSKHGQ	Terminated	Small molecular drug	[365]
Sch-45752	DME9Q3V	Terminated	Small molecular drug	[366]
SDZ-ISQ-844	DMSZJUM	Terminated	Small molecular drug	[367]
Selenotifen	DM4ESAP	Terminated	NA	[368]
SKF-96231	DMS2M58	Terminated	Small molecular drug	[369]
SM 11044	DMF0QMD	Terminated	Small molecular drug	[370]
Sulotroban	DM4SVIR	Terminated	Small molecular drug	[371]
TAK-225	DMAIUWG	Terminated	NA	[372]
Tomelukast	DM385D9	Terminated	Small molecular drug	[373]
U-78517F	DMIKI8G	Terminated	Small molecular drug	[374]
UR-8225	DMJC82N	Terminated	Small molecular drug	[375]
UR-8308	DM6C7WJ	Terminated	NA	[376]
UR-8328	DM4KOTA	Terminated	NA	[377]
VZ-564	DMYQWVK	Terminated	Small molecular drug	[378]
WIN-64821	DM960I8	Terminated	Small molecular drug	[379]
XR-12890	DMBMFD4	Terminated	NA	[380]
ZD-7717	DMJEZOP	Terminated	NA	[381]
ZD-7944	DMCT1IX	Terminated	Small molecular drug	[382]
ZM-230487	DM0TBQK	Terminated	Small molecular drug	[383]
ZT-386	DM193WR	Terminated	NA	[384]

This Disease is Treated as An Indication in 5 Preclinical Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
AZD-1678	DMY7R3X	Preclinical	NA	[305]
IMO-2134	DMXN2ZQ	Preclinical	NA	[306]
LAS-101057	DMFBMXD	Preclinical	Small molecular drug	[307]
YM-344031	DMMUYC2	Preclinical	Small molecular drug	[86]
YM-355179	DMTM1LK	Preclinical	Small molecular drug	[308]

This Disease is Treated as An Indication in 44 Investigative Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
AEOL-11207	DMH3U2E	Investigative	Small molecular drug	[385]
AG-NCA805	DME753N	Investigative	NA	[385]
AIM-101	DM5WG9N	Investigative	NA	[385]
Anti-TSLP mab	DMWK9Z5	Investigative	Monoclonal antibody	[385]
APX-E	DM3M7UG	Investigative	NA	[385]
ASOBAMAST	DM8XT1Y	Investigative	Small molecular drug	[386]
ATL-844	DM6V9SC	Investigative	Small molecular drug	[387]
BCP-1081	DMQX3SX	Investigative	NA	[385]
BFPT-12603	DMQO9R6	Investigative	NA	[385]
BW-858C	DMM2WPH	Investigative	NA	[388]
CH-3697	DM0RFTJ	Investigative	NA	[389]
CWF-0710	DMUNCPL	Investigative	NA	[385]
DS-AH-14	DMZGWQA	Investigative	NA	[390]
DW-403	DMVKEPL	Investigative	NA	[385]
ER-23006	DMAO6JS	Investigative	NA	[391]
FHT-CT4	DMU4NYN	Investigative	NA	[385]
GATA-3-specific DNAzyme	DMOQOXF	Investigative	NA	[385]
GSK-172981	DM9IZNP	Investigative	Small molecular drug	[392]
HD-101	DMLX0DX	Investigative	NA	[385]
HL-028	DMT47JB	Investigative	NA	[385]
HMPL-342	DMGWJ5K	Investigative	NA	[385]
IDR-1002	DMIR4G1	Investigative	Peptide	[393]
IW-1221	DMBTWF0	Investigative	NA	[394]
KI-0905	DM3CE86	Investigative	NA	[385]
L-873724	DMUP516	Investigative	Small molecular drug	[395]
LMS-611	DMZACFV	Investigative	NA	[385]
LPCN-1056	DMUM0HT	Investigative	NA	[385]
MAR--99	DMGF7XC	Investigative	Small molecular drug	[396]
MER-2101	DMGABLC	Investigative	NA	[385]
N-6060	DMDMI7P	Investigative	NA	[397]
NPT-CLN	DMIM0QH	Investigative	NA	[385]
OT-121	DMF1BIM	Investigative	NA	[385]
PRS-060	DM8GCHX	Investigative	NA	[398]
PXS-4159	DMHCEOU	Investigative	NA	[399]
Recombinant anti-IgE Fabs	DMCFXA6	Investigative	NA	[385]
RS-1748	DM9D8XC	Investigative	NA	[400]
RV-1088	DMI9Z2R	Investigative	NA	[385]
SP-003	DM4KRPD	Investigative	NA	[385]
Sulochrin	DMY5LA6	Investigative	Small molecular drug	[385]
TA-106	DME2PFQ	Investigative	Antibody	[401]
UR-60427	DM3YE5X	Investigative	NA	[402]
Vagonixen	DMICZQV	Investigative	NA	[385]
VALERGENT-BT	DMSZVMV	Investigative	NA	[403]
VBP	DM2A1RB	Investigative	Small molecular drug	[385]

Molecular Interaction Atlas (MIA) of This Disease

This Disease Is Related to 508 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
ACE2	TTUI5H7	Limited	Biomarker	[410]
ACKR3	TTRQJTC	Limited	Biomarker	[411]
ACTG1	TTGAZF9	Limited	Biomarker	[412]
ACVR1	TTJNBQA	Limited	Altered Expression	[413]
ACVR1B	TTPKHTZ	Limited	Biomarker	[414]
ACVR2A	TTX2DRI	Limited	Altered Expression	[415]
ADAM8	TTQWYMD	Limited	Altered Expression	[416]
ADAMTS4	TTYG6BU	Limited	Genetic Variation	[417]
ADCYAP1R1	TT5OREU	Limited	Genetic Variation	[418]
ADGRL1	TTM5OJN	Limited	Altered Expression	[419]
ADGRL3	TTQST3U	Limited	Biomarker	[420]
ADRA1B	TTBRKXS	Limited	Genetic Variation	[421]
AGER	TTMO9HF	Limited	Biomarker	[422]
AHR	TT037IE	Limited	Biomarker	[423]
ALPL	TTMR5UV	Limited	Biomarker	[424]
ANK1	TTKFPMH	Limited	Biomarker	[425]
ARRB2	TT8SO2I	Limited	Biomarker	[426]
ATF4	TTQCKWT	Limited	Biomarker	[427]
ATG7	TTLVB9Z	Limited	Genetic Variation	[428]
ATP2A2	TTE6THL	Limited	Altered Expression	[429]
ATXN2	TTPQJ7P	Limited	Genetic Variation	[430]
BCL6	TTC9YX5	Limited	Biomarker	[431]
BDKRB1	TTG5QIA	Limited	Altered Expression	[432]
BIRC2	TTQ5LRD	Limited	Biomarker	[433]
BMPR2	TTGKF90	Limited	Altered Expression	[413]
BRS3	TTKYEPM	Limited	Biomarker	[411]
CA14	TTEYTKG	Limited	Genetic Variation	[434]
CASP1	TTCQIBE	Limited	Altered Expression	[435]
CBL	TT7QT13	Limited	Altered Expression	[436]
CCR4	TT7HQD0	Limited	Biomarker	[437]
CCR6	TTFDB30	Limited	Genetic Variation	[438]
CD19	TTW640A	Limited	Biomarker	[439]
CD200	TT0BE68	Limited	Biomarker	[440]
CEACAM6	TTIGH2W	Limited	Altered Expression	[441]
CETP	TTFQAYR	Limited	Genetic Variation	[442]
CHIA	TTJB1O0	Limited	Biomarker	[443]
CHRNA5	TTH2QRX	Limited	Genetic Variation	[444]
CLDN18	TT6PKBX	Limited	Altered Expression	[445]
CLDN4	TTMTS9H	Limited	Altered Expression	[446]
CR1	TTEA8OW	Limited	Biomarker	[447]
CR2	TT0HUN7	Limited	Altered Expression	[448]
CRHR1	TT7EFHR	Limited	Genetic Variation	[449]
CRP	TTWRN6M	Limited	Biomarker	[450]
CRYZ	TTP6UO8	Limited	Biomarker	[451]
CSF2RA	TT6MP2Z	Limited	Altered Expression	[452]
CTSG	TTQAJF1	Limited	Genetic Variation	[453]
CX3CL1	TT1OFBQ	Limited	Biomarker	[454]
CX3CR1	TT2T98G	Limited	Genetic Variation	[455]
CXCL10	TTQOVYA	Limited	Biomarker	[456]
CXCL11	TTWG0RE	Limited	Biomarker	[457]
CXCR1	TTMWT8Z	Limited	Genetic Variation	[458]
CYP11A1	TTSYVO6	Limited	Biomarker	[459]
CYP24A1	TT82UI1	Limited	Altered Expression	[448]
CYP2J2	TTNE1C7	Limited	Biomarker	[460]
DLL1	TT9CFQD	Limited	Genetic Variation	[461]
DLL4	TTV23LH	Limited	Biomarker	[462]
DUSP1	TTG8HIM	Limited	Altered Expression	[463]
EDNRA	TTKRD0G	Limited	Biomarker	[411]
EIF2AK2	TTXEZJ4	Limited	Biomarker	[464]
EIF2AK3	TT79U1M	Limited	Biomarker	[427]
ENTPD1	TTYM8DJ	Limited	Altered Expression	[465]
ERBB2	TTR5TV4	Limited	Biomarker	[466]
ERBB3	TTSINU2	Limited	Genetic Variation	[467]
EREG	TTYSB89	Limited	Genetic Variation	[468]
ESRRB	TTKF0XS	Limited	Biomarker	[469]
ETS2	TT9AH0M	Limited	Genetic Variation	[470]
EZR	TTE47YC	Limited	Altered Expression	[471]
F10	TTCIHJA	Limited	Biomarker	[472]
F13A1	TTXI2RA	Limited	Biomarker	[473]
F2RL1	TTQR74A	Limited	Biomarker	[474]
F3	TT38MDJ	Limited	Biomarker	[475]
FCER2	TTCH6MU	Limited	Biomarker	[476]
FER	TTRA9G0	Limited	Genetic Variation	[477]
FFAR2	TT0FYAN	Limited	Altered Expression	[478]
FFAR3	TTXDOHN	Limited	Altered Expression	[478]
FGF1	TTMY81X	Limited	Biomarker	[479]
FOXP3	TT1X3QF	Limited	Biomarker	[480]
FPR2	TTOJ1NF	Limited	Biomarker	[481]
FSTL3	TTWRPM8	Limited	Biomarker	[482]
GCG	TT6Y4PN	Limited	Biomarker	[483]
GCLM	TTNFESW	Limited	Genetic Variation	[484]
GLA	TTIS03D	Limited	Biomarker	[485]
GLB1	TTNGJPH	Limited	Genetic Variation	[486]
GNAO1	TTAXD8Z	Limited	Biomarker	[487]
GPR183	TTME5YJ	Limited	Biomarker	[488]
GPR35	TT254XD	Limited	Biomarker	[489]
GPRC6A	TTI1PRE	Limited	Biomarker	[490]
GRK2	TTAZ3MN	Limited	Biomarker	[491]
GRK5	TTTCXO0	Limited	Genetic Variation	[492]
GRM1	TTVBPDM	Limited	Genetic Variation	[493]
GSTA1	TT4P8DE	Limited	Biomarker	[494]
GSTO1	TTWO3SH	Limited	Genetic Variation	[495]
HDAC2	TTSHTOI	Limited	Altered Expression	[496]
HDAC7	TTMUEK1	Limited	Genetic Variation	[486]
HEXB	TTKIBKM	Limited	Altered Expression	[497]
HLA-DQA1	TTU2I3J	Limited	Genetic Variation	[486]
HLA-DQB2	TTL7VOU	Limited	Biomarker	[487]
HMGB1	TTWQYB7	Limited	Biomarker	[498]
HMOX1	TTI6V2A	Limited	Biomarker	[499]
HRH4	TTXJ178	Limited	Genetic Variation	[500]
HSPA12B	TTAI9ZQ	Limited	Biomarker	[501]
HTR4	TT07C3Y	Limited	Biomarker	[502]
ID2	TTW8A5N	Limited	Genetic Variation	[503]
IFNAR2	TTMQB37	Limited	Genetic Variation	[504]
IFNB1	TT4TZ8J	Limited	Biomarker	[505]
IFNGR2	TT13TL0	Limited	Biomarker	[506]
IFNL1	TTM624L	Limited	Altered Expression	[507]
IKZF3	TTCZVFZ	Limited	Genetic Variation	[508]
IL11	TTGUYTR	Limited	Altered Expression	[509]
IL12RB2	TT4SWR8	Limited	Biomarker	[504]
IL17D	TTC5LTG	Limited	Biomarker	[510]
IL17F	TT2B6PS	Limited	Altered Expression	[511]
IL2	TTF89GD	Limited	Biomarker	[512]
IL21R	TTZO9B0	Limited	Biomarker	[513]
IL25	TTVMO5W	Limited	Altered Expression	[514]
IL37	TTQTX98	Limited	Biomarker	[515]
IL5RA	TTXH9AD	Limited	Biomarker	[516]
IL7	TT8FRMO	Limited	Altered Expression	[517]
IRAK3	TTBPJOK	Limited	Biomarker	[518]
IRF3	TTYR7OH	Limited	Biomarker	[519]
ITGA4	TTJMF9P	Limited	Altered Expression	[520]
ITGA8	TT1FW8B	Limited	Genetic Variation	[442]
ITGAL	TT48WR6	Limited	Altered Expression	[521]
ITGB7	TTLT9XQ	Limited	Biomarker	[522]
ITGB8	TTIF29E	Limited	Genetic Variation	[486]
ITK	TT3C80U	Limited	Biomarker	[523]
JAG2	TTOJY1B	Limited	Biomarker	[524]
JMJD1C	TTBISK4	Limited	Genetic Variation	[477]
KIF11	TTBGTCW	Limited	Genetic Variation	[486]
KNG1	TTDJ4MY	Limited	Biomarker	[525]
LANCL1	TTZW8NS	Limited	Altered Expression	[526]
LBP	TTVQJLY	Limited	Altered Expression	[527]
LCT	TTA0OSE	Limited	Biomarker	[528]
LILRB4	TTREOKA	Limited	Biomarker	[529]
LIPA	TTS8T1M	Limited	Biomarker	[530]
LNPEP	TTY2KP7	Limited	Biomarker	[531]
LPAR3	TTE2YJR	Limited	Biomarker	[490]
LTA4H	TTXZEAJ	Limited	Biomarker	[532]
LTC4S	TTW7OTG	Limited	Biomarker	[533]
LY96	TT8S9AV	Limited	Genetic Variation	[534]
MAP3K1	TTW8TJI	Limited	Genetic Variation	[535]
MAP4K4	TT6NI13	Limited	Genetic Variation	[536]
MAPK9	TT3IVG2	Limited	Biomarker	[537]
MARCKS	TTHRM39	Limited	Posttranslational Modification	[538]
MARK2	TTAJ45Y	Limited	Altered Expression	[539]
MAS1	TTOISYB	Limited	Biomarker	[540]
MC4R	TTD0CIQ	Limited	Genetic Variation	[541]
MFGE8	TT1GLAJ	Limited	Altered Expression	[542]
MKNK1	TTEZAUX	Limited	Biomarker	[543]
MRGPRX1	TTIX6PK	Limited	Biomarker	[490]
MRGPRX2	TT3YV20	Limited	Biomarker	[544]
MSR1	TT2TDH9	Limited	Biomarker	[545]
MUC15	TTGQ6MI	Limited	Genetic Variation	[546]
MYD88	TTB6Q2O	Limited	Biomarker	[498]
MYLK	TT18ETS	Limited	Biomarker	[547]
NEDD9	TT1UREA	Limited	Altered Expression	[548]
NGF	TTDN3LF	Limited	Altered Expression	[549]
NLRP3	TT4EN8X	Limited	Biomarker	[550]
NOD2	TTYPUHA	Limited	Genetic Variation	[551]
NRG1	TTEH395	Limited	Biomarker	[552]
NTF3	TTZHKV9	Limited	Biomarker	[553]
OPRK1	TTQW87Y	Limited	Biomarker	[554]
OPRL1	TTNT7K8	Limited	Biomarker	[555]
ORAI1	TTE76YK	Limited	Biomarker	[556]
OXTR	TTSCIUP	Limited	Biomarker	[557]
P2RY12	TTZ1DT0	Limited	Genetic Variation	[558]
PDE4A	TTZ97H5	Limited	Biomarker	[559]
PDE4D	TTSKMI8	Limited	Genetic Variation	[560]
PDGFA	TTSM78N	Limited	Genetic Variation	[561]
PEBP1	TT1BGU8	Limited	Biomarker	[562]
PF4	TTSG7Q5	Limited	Biomarker	[563]
PGD	TTZ3IFB	Limited	Altered Expression	[564]
PLA2G2A	TTO8QRU	Limited	Biomarker	[565]
PLA2G4C	TTBYG4O	Limited	Biomarker	[566]
PLAU	TTGY7WI	Limited	Biomarker	[567]
PLD1	TT3T17P	Limited	Biomarker	[568]
PRKCE	TT57MT2	Limited	Genetic Variation	[438]
PRKCQ	TT1MS7X	Limited	Genetic Variation	[486]
PTGIR	TTOFYT1	Limited	Genetic Variation	[569]
RBP4	TT0C8BY	Limited	Biomarker	[570]
RBPJ	TT72D4Z	Limited	Biomarker	[571]
RGS4	TTGTKX9	Limited	Altered Expression	[572]
ROBO1	TTND1YP	Limited	Biomarker	[573]
RORA	TT1TYN7	Limited	Genetic Variation	[508]
S1PR1	TT9JZCK	Limited	Biomarker	[574]
S1PR3	TTDYP7I	Limited	Biomarker	[575]
SAA1	TTY0DN9	Limited	Genetic Variation	[576]
SCD	TT6RIOV	Limited	Biomarker	[577]
SCN8A	TT54ERL	Limited	Biomarker	[578]
SELL	TT2IYXF	Limited	Altered Expression	[579]
SEMA3A	TTVKD3S	Limited	Biomarker	[580]
SEMA4D	TT5UT28	Limited	Biomarker	[581]
SLC17A5	TTFSUIA	Limited	Biomarker	[582]
SLC26A4	TT7X02I	Limited	Altered Expression	[583]
SLC26A9	TTKRVU0	Limited	Biomarker	[584]
SLC27A4	TT20AYF	Limited	Biomarker	[585]
SLC8A1	TTCF82X	Limited	Biomarker	[586]
SLCO2B1	TTDL3UZ	Limited	Genetic Variation	[587]
SMN1	TT8QL6X	Limited	Altered Expression	[588]
SMPD1	TTJTM88	Limited	Biomarker	[589]
SPDEF	TT2ZUPY	Limited	Altered Expression	[590]
STOML2	TTOI329	Limited	Altered Expression	[431]
TAGLN	TTDRZ9H	Limited	Altered Expression	[591]
TAGLN2	TTP6BIJ	Limited	Altered Expression	[592]
TBL1X	TTAL6S1	Limited	Biomarker	[593]
TBL1XR1	TTYXT16	Limited	Genetic Variation	[486]
TBXA2R	TT2O84V	Limited	Genetic Variation	[594]
TFRC	TT8MG4S	Limited	Genetic Variation	[486]
TLN1	TTQSMFG	Limited	Genetic Variation	[554]
TMEM219	TTY078U	Limited	Biomarker	[595]
TNFAIP3	TT5W0IO	Limited	Biomarker	[596]
TNFRSF18	TTG6LA7	Limited	Biomarker	[597]
TNFRSF4	TTL31H0	Limited	Altered Expression	[598]
TNFSF13B	TTWMIDN	Limited	Altered Expression	[599]
TPSD1	TTNWD8O	Limited	Altered Expression	[600]
TRPA1	TTELV3W	Limited	Biomarker	[601]
TRPC1	TTA76X0	Limited	Biomarker	[602]
TRPC3	TTNVC34	Limited	Altered Expression	[603]
TRPM7	TTFPVZO	Limited	Biomarker	[604]
TRPM8	TTXDKTO	Limited	Biomarker	[605]
TRPV1	TTMI6F5	Limited	Altered Expression	[606]
WNT7A	TT8NARC	Limited	Altered Expression	[607]
CTSA	TT5NILS	Disputed	Biomarker	[608]
DDX58	TTVB0O3	Disputed	Biomarker	[609]
DUSP10	TTF3RJ0	Disputed	Biomarker	[610]
EDN2	TTMR0OP	Disputed	Biomarker	[611]
IGFBP1	TTCJTWF	Disputed	Biomarker	[612]
ITCH	TT5SEWD	Disputed	Genetic Variation	[613]
LMO2	TTFX379	Disputed	Posttranslational Modification	[614]
MTTP	TTUS1RD	Disputed	Biomarker	[615]
PDGFD	TTSN0GA	Disputed	Genetic Variation	[616]
PGRMC1	TTY3LAZ	Disputed	Genetic Variation	[617]
POR	TTOQ9GZ	Disputed	Genetic Variation	[618]
SOCS3	TTI0ME6	Disputed	Biomarker	[619]
STC1	TTDLUER	Disputed	Biomarker	[620]
TBK1	TTMP03S	Disputed	Biomarker	[621]
TRIM37	TTAMCSL	Disputed	Biomarker	[622]
ADORA2A	TTM2AOE	moderate	Altered Expression	[623]
AGR2	TT9K86S	moderate	Altered Expression	[624]
AKR1B1	TTFBNVI	moderate	Genetic Variation	[625]
ANGPT1	TTWNQ1T	moderate	Biomarker	[540]
ANO1	TTOJI4S	moderate	Biomarker	[626]
AOAH	TT2EJXQ	moderate	Biomarker	[627]
AXL	TTZPY6J	moderate	Posttranslational Modification	[628]
C3AR1	TTI6B3F	moderate	Biomarker	[629]
CALCA	TTVSFJW	moderate	Biomarker	[630]
CCL21	TTLZK1U	moderate	Biomarker	[631]
CCL22	TTBTWI1	moderate	Biomarker	[632]
CCL3	TT8I4WB	moderate	Biomarker	[633]
CCR7	TT2GIDQ	moderate	Biomarker	[634]
CD163	TTTZ9DE	moderate	Biomarker	[635]
CD69	TTPQE9F	moderate	Biomarker	[636]
CDK2	TT7HF4W	moderate	Genetic Variation	[637]
CHRM1	TTZ9SOR	moderate	Genetic Variation	[638]
CHRM2	TTYEG6Q	moderate	Genetic Variation	[638]
CHRNA2	TTF4E0J	moderate	Genetic Variation	[639]
CRHR2	TTIY658	moderate	Biomarker	[640]
CRLF2	TTRMZ0N	moderate	Biomarker	[641]
CTSS	TTUMQVO	moderate	Genetic Variation	[642]
CYP1A2	TTS1DTU	moderate	Genetic Variation	[643]
EBI3	TTJF68X	moderate	Genetic Variation	[644]
EPHA5	TTV9KOD	moderate	Genetic Variation	[645]
ERBB4	TTWALCO	moderate	Genetic Variation	[646]
ETS1	TTTGPSD	moderate	Genetic Variation	[647]
FCER1G	TTDGEC0	moderate	Genetic Variation	[486]
FCGRT	TTKLPHO	moderate	Genetic Variation	[648]
FDXR	TT3W4IX	moderate	Genetic Variation	[649]
FKBP4	TTHY0FT	moderate	Altered Expression	[650]
GABRQ	TTXDUR9	moderate	Genetic Variation	[651]
GAPDH	TTUGSWA	moderate	Altered Expression	[652]
GGT1	TTZVT7O	moderate	Genetic Variation	[653]
GLI2	TT045OH	moderate	Genetic Variation	[654]
GNAI1	TTL1HWR	moderate	Genetic Variation	[442]
HLA-B	TTGS10J	moderate	Genetic Variation	[486]
IL12A	TTRTK6Y	moderate	Genetic Variation	[655]
IL18RAP	TTZUJVE	moderate	Genetic Variation	[656]
IRAK1	TTXAJWN	moderate	Altered Expression	[657]
IRAK4	TTILUKB	moderate	Genetic Variation	[658]
ITGAM	TTB69FJ	moderate	Genetic Variation	[659]
JAK3	TTT7PJU	moderate	Posttranslational Modification	[660]
KCNQ5	TTWVL5Q	moderate	Genetic Variation	[661]
KLK3	TTS78AZ	moderate	Altered Expression	[662]
KLKB1	TTN0PCX	moderate	Genetic Variation	[663]
LAG3	TTNVXAW	moderate	Biomarker	[664]
LIF	TTGZ5WN	moderate	Altered Expression	[665]
LRRK2	TTK0FEA	moderate	Genetic Variation	[647]
MCAM	TTHRE05	moderate	Altered Expression	[666]
MMP10	TTXLEG7	moderate	Biomarker	[667]
MUC1	TTBHFYQ	moderate	Biomarker	[668]
MUSK	TT6SA0X	moderate	Altered Expression	[669]
NLRP1	TTQX29T	moderate	Biomarker	[566]
NOTCH4	TTXDIK2	moderate	Biomarker	[670]
NR0B2	TT25A9Q	moderate	Altered Expression	[671]
NR4A3	TTJQB49	moderate	Genetic Variation	[672]
NTF4	TTIM2WO	moderate	Biomarker	[673]
OSM	TTIVXSE	moderate	Biomarker	[674]
P2RX7	TT473XN	moderate	Biomarker	[675]
PDE11A	TTTWC79	moderate	Genetic Variation	[676]
PIK3CD	TTGBPJE	moderate	Biomarker	[677]
PIN1	TTJNTSI	moderate	Altered Expression	[678]
PLA2G7	TTDNFMT	moderate	Biomarker	[679]
PLAUR	TTNOSTX	moderate	Biomarker	[680]
PMEL	TT8MK59	moderate	Genetic Variation	[637]
PPARGC1B	TTKSQ3W	moderate	Altered Expression	[436]
PRKG1	TT7IZSA	moderate	Genetic Variation	[681]
PRMT1	TTVOJAI	moderate	Altered Expression	[682]
PROC	TTZUXYS	moderate	Genetic Variation	[681]
PSMB6	TT8EPLT	moderate	Genetic Variation	[461]
PTGES	TTYLQ8V	moderate	Biomarker	[477]
PTPN2	TTY8PUS	moderate	Genetic Variation	[647]
PTPN6	TT369M5	moderate	Altered Expression	[671]
PTPRC	TTUS45N	moderate	Genetic Variation	[486]
RUNX1	TTWIN3H	moderate	Genetic Variation	[486]
S100A9	TT0TMQG	moderate	Biomarker	[683]
SELE	TT1PL7M	moderate	Genetic Variation	[684]
SELP	TTE5VG0	moderate	Biomarker	[685]
SLC22A2	TT0XOJN	moderate	Biomarker	[686]
SLC30A8	TTXIGT7	moderate	Genetic Variation	[687]
SLC6A12	TTQBMPI	moderate	Genetic Variation	[442]
SMAD3	TTHQZV7	moderate	Genetic Variation	[688]
SOX5	TTXHSZK	moderate	Genetic Variation	[689]
TACR2	TTYO0A3	moderate	Biomarker	[690]
THBD	TTAPV67	moderate	Biomarker	[691]
TLR3	TTD24Y0	moderate	Biomarker	[692]
TLR6	TTWRI8V	moderate	Genetic Variation	[467]
TNFRSF11A	TT3K9S2	moderate	Genetic Variation	[486]
TNFRSF13B	TTL9OD4	moderate	Genetic Variation	[693]
TNFRSF9	TTPW9LJ	moderate	Biomarker	[694]
TNFSF15	TTEST6I	moderate	Biomarker	[695]
TRAF6	TTCDR6M	moderate	Altered Expression	[657]
TREM1	TTHZQP0	moderate	Biomarker	[696]
TSPO	TTPTXIN	moderate	Biomarker	[697]
TXNRD3	TTDYFVB	moderate	Biomarker	[698]
ADA	TTLP57V	Strong	Biomarker	[699]
ADAM10	TTVXEGU	Strong	Biomarker	[700]
ADCY2	TTBQ9IM	Strong	Biomarker	[701]
ADORA1	TTK25J1	Strong	Genetic Variation	[486]
ADRA1A	TTNGILX	Strong	Biomarker	[411]
ADRA2B	TTWM4TY	Strong	Biomarker	[411]
AGTR2	TTQVOEI	Strong	Biomarker	[702]
AGXT	TTF5NVW	Strong	Biomarker	[703]
ALDH2	TTFLN4T	Strong	Genetic Variation	[704]
ALOX15	TTN9T81	Strong	Biomarker	[705]
AOC1	TTM3B5R	Strong	Genetic Variation	[706]
AREG	TT76B3W	Strong	Altered Expression	[707]
ARG2	TTV1AG6	Strong	Altered Expression	[708]
ARSA	TTYQANR	Strong	Genetic Variation	[709]
BDKRB2	TTGY8IW	Strong	Biomarker	[710]
BLK	TTNDSC3	Strong	Biomarker	[711]
C3	TTJGY7A	Strong	Genetic Variation	[712]
C5	TTKANGO	Strong	Genetic Variation	[713]
CAMP	TTULOB6	Strong	Altered Expression	[714]
CARM1	TTIZQFJ	Strong	Biomarker	[715]
CASP10	TTX5HEK	Strong	Biomarker	[716]
CCL20	TT2XAZY	Strong	Biomarker	[575]
CCR1	TTC24WT	Strong	Altered Expression	[717]
CCR2	TTFZYTO	Strong	Biomarker	[718]
CCR8	TTE836A	Strong	Biomarker	[719]
CCR9	TTIPS8B	Strong	Biomarker	[720]
CD160	TTOFEAS	Strong	Biomarker	[721]
CD2	TTJDUNO	Strong	Altered Expression	[722]
CD276	TT6CQUM	Strong	Biomarker	[723]
CD28	TTQ13FT	Strong	Altered Expression	[598]
CD33	TTJVYO3	Strong	Genetic Variation	[724]
CD34	TTZAVYN	Strong	Altered Expression	[725]
CD38	TTPURFN	Strong	Biomarker	[726]
CD86	TT53XHB	Strong	Biomarker	[727]
CHAT	TTKYFSB	Strong	Biomarker	[728]
CHRM3	TTQ13Z5	Strong	Biomarker	[697]
CPB2	TTP18AY	Strong	Altered Expression	[729]
CREB1	TTH4AN3	Strong	Altered Expression	[730]
CSF2RB	TTPYS82	Strong	Biomarker	[731]
CXCL9	TTWE5PB	Strong	Biomarker	[456]
CXCR2	TT30C9G	Strong	Biomarker	[732]
CXCR3	TT1UCIJ	Strong	Biomarker	[733]
CXCR6	TT2BVUA	Strong	Biomarker	[411]
CYP2C19	TTZ58XG	Strong	Biomarker	[734]
CYSLTR2	TT0PZR5	Strong	Genetic Variation	[735]
DCLK3	TTMYK4Z	Strong	Biomarker	[736]
DCN	TTB3XAN	Strong	Biomarker	[737]
DNMT1	TT6S2FE	Strong	Biomarker	[738]
DPP10	TTOVUPC	Strong	Biomarker	[739]
DPP4	TTDIGC1	Strong	Biomarker	[740]
DTL	TT8396I	Strong	Biomarker	[736]
EDN1	TTJR60Z	Strong	Altered Expression	[741]
EDNRB	TT3ZTGU	Strong	Genetic Variation	[742]
ELANE	TTPLTSQ	Strong	Biomarker	[743]
EPX	TTCIO0M	Strong	Genetic Variation	[516]
F7	TTF0EGX	Strong	Therapeutic	[744]
FABP1	TTIV96N	Strong	Genetic Variation	[745]
FADS2	TTT2VDU	Strong	Genetic Variation	[746]
FAS	TT7LTUJ	Strong	Biomarker	[597]
FCGR2A	TTXT21W	Strong	Biomarker	[747]
FCGR3A	TTIFOC0	Strong	Altered Expression	[579]
FKBP5	TT0J5KQ	Strong	Biomarker	[748]
FOS	TTOM5AU	Strong	Biomarker	[749]
FOSL1	TTY8LZG	Strong	Biomarker	[750]
FYN	TT2B9KF	Strong	Genetic Variation	[751]
HMGCR	TTPADOQ	Strong	Altered Expression	[752]
HRH1	TTTIBOJ	Strong	Genetic Variation	[753]
HSP90AB1	TTH5YN2	Strong	Biomarker	[754]
ICAM1	TTA1L39	Strong	Genetic Variation	[755]
ICOS	TTE5VP6	Strong	Biomarker	[756]
ICOSLG	TTB9Z8R	Strong	Altered Expression	[757]
IL13RA1	TTNEAMG	Strong	Altered Expression	[758]
IL19	TT87RWS	Strong	Biomarker	[759]
IL1R1	TTWOTEA	Strong	Genetic Variation	[746]
IL1RN	TT6GSR3	Strong	Biomarker	[456]
IL21	TT9QEJ6	Strong	Biomarker	[513]
IL23A	TTC1GLB	Strong	Altered Expression	[760]
IL23R	TT6H4QR	Strong	Genetic Variation	[761]
IL2RA	TT10Y9E	Strong	Biomarker	[480]
IL2RB	TT9721Y	Strong	Genetic Variation	[762]
IL31	TT1RJXK	Strong	Altered Expression	[763]
IL32	TTD4G7L	Strong	Biomarker	[764]
IL7R	TTAWI51	Strong	Genetic Variation	[467]
INHBA	TTVB30D	Strong	Altered Expression	[765]
IRF1	TT4TU3L	Strong	Biomarker	[646]
ITGB3	TTJA1ZO	Strong	Altered Expression	[766]
ITGB6	TTKQSXZ	Strong	Biomarker	[767]
ITPR1	TT5HWAT	Strong	Biomarker	[768]
ITPR3	TTH1769	Strong	Genetic Variation	[746]
JUN	TTS7IR5	Strong	Biomarker	[749]
KITLG	TTDJ51N	Strong	Biomarker	[769]
KLK1	TT5T3P6	Strong	Biomarker	[770]
KRT19	TT3JF9E	Strong	Biomarker	[771]
LGALS3	TTFPQV7	Strong	Biomarker	[772]
LPAR2	TTB7Y8I	Strong	Biomarker	[411]
LRRC32	TT0FAYT	Strong	Genetic Variation	[773]
LTB4R2	TTVJX54	Strong	Biomarker	[774]
MAPKAPK2	TTMUG9D	Strong	Biomarker	[775]
MIF	TT6804T	Strong	Biomarker	[776]
MMP1	TTMX39J	Strong	Altered Expression	[777]
MMP8	TTGA1IV	Strong	Biomarker	[778]
MRC1	TTKV8W5	Strong	Biomarker	[641]
MTNR1A	TT0WAIE	Strong	Genetic Variation	[779]
MUC5AC	TTEL90S	Strong	Biomarker	[780]
MYB	TT8V13P	Strong	Genetic Variation	[781]
NOD1	TTYSRXM	Strong	Altered Expression	[782]
NQO1	TT8XK6L	Strong	Genetic Variation	[783]
NR1I2	TT7LCTF	Strong	Biomarker	[474]
NTRK1	TTTDVOJ	Strong	Genetic Variation	[673]
OXER1	TT7WBSV	Strong	Biomarker	[490]
PARP1	TTVDSZ0	Strong	Biomarker	[784]
PDE4B	TTVIAT9	Strong	Biomarker	[567]
PDE7A	TT1BC3A	Strong	Biomarker	[785]
PDGFB	TTQA6SX	Strong	Biomarker	[786]
PIM2	TT69J2Z	Strong	Biomarker	[787]
PINX1	TT4FJ3A	Strong	Altered Expression	[788]
PLA2G4A	TTT1JVS	Strong	Biomarker	[789]
PLA2R1	TTHKW7D	Strong	Biomarker	[790]
PLCG1	TT6T4JI	Strong	Altered Expression	[791]
PNPLA3	TTEUAEH	Strong	Genetic Variation	[792]
PPP2CA	TTHTKNY	Strong	Biomarker	[793]
PRMT3	TTL4XSQ	Strong	Biomarker	[715]
PRMT5	TTR1D7X	Strong	Biomarker	[715]
PTAFR	TTQL5VC	Strong	Biomarker	[794]
PTEN	TTXJ3W7	Strong	Genetic Variation	[795]
PTGER3	TTPNGDE	Strong	Therapeutic	[796]
RGS2	TTKB7T3	Strong	Altered Expression	[797]
RHOA	TTP2U16	Strong	Altered Expression	[795]
RIPK2	TTCQ2E5	Strong	Altered Expression	[798]
S100A8	TT4AF6N	Strong	Biomarker	[714]
SERPING1	TTVQ6R9	Strong	Biomarker	[799]
SIK2	TTCUGZR	Strong	Genetic Variation	[746]
SLC18A3	TTV8KWS	Strong	Biomarker	[728]
SLC22A1	TTM5Q4V	Strong	Biomarker	[728]
SLC5A7	TTRV7W3	Strong	Biomarker	[728]
SLC6A15	TT4LRUE	Strong	Genetic Variation	[800]
SLC6A7	TT9LGO5	Strong	Biomarker	[801]
SSTR4	TTAE1BR	Strong	Biomarker	[411]
STAT1	TTN7R6K	Strong	Posttranslational Modification	[802]
TACR1	TTZPO1L	Strong	Biomarker	[544]
TAP1	TT7JZI8	Strong	Genetic Variation	[803]
TBXAS1	TTKNWZ4	Strong	Biomarker	[804]
TGFB2	TTI0KH6	Strong	Altered Expression	[805]
TLR1	TTW14D0	Strong	Genetic Variation	[806]
TNC	TTUCPMY	Strong	Biomarker	[692]
TNFRSF8	TT2GM5R	Strong	Biomarker	[807]
TNFSF14	TTKVENM	Strong	Altered Expression	[808]
TPSAB1	TTM1TDX	Strong	Altered Expression	[809]
TPT1	TT3PTB6	Strong	Biomarker	[810]
TYRO3	TTIEMFN	Strong	Genetic Variation	[811]
UTS2	TTERU0T	Strong	Altered Expression	[812]
VIP	TTGTWLF	Strong	Biomarker	[813]
VSIR	TT51SK8	Strong	Biomarker	[814]
ABCA1	TTJW1GN	Definitive	Biomarker	[815]
ABCC9	TTEF5MJ	Definitive	Biomarker	[816]
ACKR1	TTKY2NS	Definitive	Altered Expression	[808]
ALDH3A2	TTB6UM0	Definitive	Biomarker	[817]
C9orf72	TTA4SHR	Definitive	Biomarker	[818]
CLCA1	TT3AF4R	Definitive	Biomarker	[819]
CLN3	TTORF9W	Definitive	Biomarker	[820]
FOSL2	TT689IR	Definitive	Altered Expression	[821]
GOT1	TTU507L	Definitive	Biomarker	[423]
HLA-G	TTLKFB3	Definitive	Genetic Variation	[822]
HSD11B2	TT9H85R	Definitive	Biomarker	[823]
ISG15	TTVOH3T	Definitive	Biomarker	[824]
NRP2	TTRXUVC	Definitive	Biomarker	[825]
RHO	TTH0KSX	Definitive	Biomarker	[826]
RUNX3	TTKCVO7	Definitive	Altered Expression	[827]
SCN10A	TT90XZ8	Definitive	Biomarker	[824]
SERPINB3	TT6QLPX	Definitive	Biomarker	[828]
SLC38A1	TT1YE9Z	Definitive	Biomarker	[829]
SLC38A2	TTUSC27	Definitive	Genetic Variation	[829]
SRR	TTZFUY6	Definitive	Altered Expression	[830]
TFF1	TTNOJIZ	Definitive	Biomarker	[831]
TNFRSF14	TTWGTC1	Definitive	Biomarker	[808]

This Disease Is Related to 14 DTP Molecule(s)

Gene Name	DTP ID	Evidence Level	Mode of Inheritance	REF
SLC12A2	DTHKL3Q	Limited	Biomarker	[832]
SLC16A7	DTLT3UG	Limited	Genetic Variation	[438]
SLC22A4	DT2EG60	Limited	Genetic Variation	[833]
SLC24A3	DTO18LP	Limited	Biomarker	[586]
SLC25A20	DTQOUM4	Limited	Genetic Variation	[834]
SLC2A10	DT3BI6S	Limited	Genetic Variation	[835]
SLC45A2	DTNCJAT	Limited	Biomarker	[836]
SLC7A2	DTWY9RT	Limited	Genetic Variation	[438]
ABCD1	DTKM9DZ	moderate	Genetic Variation	[837]
SLC5A12	DTM301H	moderate	Genetic Variation	[442]
SLC22A5	DT3HUVD	Strong	Biomarker	[838]
SLC26A3	DTN1FMD	Strong	Biomarker	[839]
SLC52A1	DT7NOKR	Strong	Biomarker	[474]
SLC5A8	DTE3TAW	Strong	Altered Expression	[840]

This Disease Is Related to 29 DME Molecule(s)

Gene Name	DME ID	Evidence Level	Mode of Inheritance	REF
CYP27A1	DEBS639	Limited	Genetic Variation	[841]
CYP27B1	DE3FYEM	Limited	Biomarker	[842]
CYP2C8	DES5XRU	Limited	Altered Expression	[843]
CYP4F3	DEFCMPI	Limited	Biomarker	[460]
EGLN3	DEMQTKH	Limited	Altered Expression	[844]
GNPDA2	DEPJGQB	Limited	Genetic Variation	[541]
INPP4A	DEBJ2NL	Limited	Biomarker	[845]
NADSYN1	DELF8BA	Limited	Genetic Variation	[846]
PON2	DEHJU7E	Limited	Biomarker	[847]
PTGDS	DER3H9C	Limited	Altered Expression	[848]
SAT1	DEMWO83	Limited	Biomarker	[849]
SMOX	DEOH5V3	Limited	Biomarker	[849]
UBASH3B	DE10BJ5	Limited	Biomarker	[850]
UGT1A3	DEF2WXN	Limited	Biomarker	[851]
UGT1A6	DESD26P	Limited	Genetic Variation	[852]
ABO	DESIA7R	moderate	Biomarker	[853]
ADH5	DEIOH6A	moderate	Biomarker	[854]
CPA4	DEXKD7J	moderate	Biomarker	[855]
GSTO2	DEHMPZR	moderate	Genetic Variation	[494]
MAT2B	DEKF1OH	moderate	Biomarker	[698]
MMEL1	DEYCUQ2	moderate	Genetic Variation	[647]
CYP2R1	DEBIHM3	Strong	Genetic Variation	[856]
FADS1	DE05S8C	Strong	Genetic Variation	[746]
GLDC	DEIN8FB	Strong	Genetic Variation	[746]
MANBA	DEMH6UB	Strong	Genetic Variation	[746]
NAT1	DE7OAB3	Strong	Genetic Variation	[857]
NAT2	DER7TA0	Strong	Genetic Variation	[858]
SCLY	DEH4TD6	Strong	Biomarker	[859]
SULT1A3	DEP7E8X	Strong	Biomarker	[860]

This Disease Is Related to 686 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
A2M	OTFTX90K	Limited	Biomarker	[861]
AANAT	OTUBJ7SX	Limited	Biomarker	[862]
ACAA1	OTVKRET0	Limited	Genetic Variation	[863]
ACAD8	OT3JI5GB	Limited	Genetic Variation	[864]
ACMSD	OTPSXPSF	Limited	Genetic Variation	[442]
ACOT7	OT7C68YV	Limited	Biomarker	[412]
ACTA1	OTOVGLPG	Limited	Biomarker	[865]
ACTBL2	OTD6B81U	Limited	Biomarker	[412]
ACTG2	OTRDWUO0	Limited	Biomarker	[412]
ADA2	OTGCV24S	Limited	Biomarker	[866]
ADAM12	OTZKOTDB	Limited	Biomarker	[867]
ADAMTS14	OTFJ1PDB	Limited	Genetic Variation	[868]
ADAMTS9	OTV3Q0DS	Limited	Genetic Variation	[869]
ADAMTSL1	OTBNYF3F	Limited	Genetic Variation	[442]
ADCY9	OT1IZT5K	Limited	Biomarker	[870]
ADGRA1	OTXL5IFH	Limited	Biomarker	[871]
AFM	OTPOR8IO	Limited	Biomarker	[872]
AGO2	OT4JY32Q	Limited	Biomarker	[873]
AHNAK	OT6KH1WG	Limited	Genetic Variation	[874]
AIFM1	OTKPWB7Q	Limited	Biomarker	[875]
AKAP13	OTOZAR14	Limited	Altered Expression	[876]
ALDH7A1	OTV57BZD	Limited	Altered Expression	[877]
ALOX15B	OTWQQ08W	Limited	Altered Expression	[878]
ANKEF1	OTFH7ZM3	Limited	Biomarker	[879]
ANO3	OTM34U6Q	Limited	Genetic Variation	[546]
ANXA4	OTUCRYXL	Limited	Genetic Variation	[880]
ANXA6	OT9KIQ0Y	Limited	Biomarker	[850]
AP1S3	OTPCMV24	Limited	Genetic Variation	[486]
AP2A2	OTD1UGUN	Limited	Genetic Variation	[477]
AP3B1	OTYTIH5Q	Limited	Genetic Variation	[442]
APBB3	OTNUTR0N	Limited	Biomarker	[545]
APOBR	OT9EUZX3	Limited	Biomarker	[881]
ARHGAP24	OTCQCEZS	Limited	Genetic Variation	[442]
ARHGEF12	OTM2D3LT	Limited	Biomarker	[882]
ARMH1	OTTJC0D6	Limited	Altered Expression	[526]
ARRDC1	OTMCTFHC	Limited	Genetic Variation	[430]
ATP2A3	OTFYDEES	Limited	Biomarker	[481]
ATP5F1B	OTLFZUQK	Limited	Altered Expression	[883]
ATPAF1	OTG1V44F	Limited	Genetic Variation	[884]
ATRN	OTTCLOPV	Limited	Genetic Variation	[442]
BACH2	OT17GS18	Limited	Genetic Variation	[486]
BEST1	OTWHE1ZC	Limited	Altered Expression	[885]
BID	OTOSHSHU	Limited	Biomarker	[886]
BMPR1B	OTGFN0OD	Limited	Altered Expression	[413]
BNC2	OTU22H9Z	Limited	Genetic Variation	[442]
BPIFA1	OTQFD2J5	Limited	Biomarker	[887]
BTNL2	OTTTEMZA	Limited	Genetic Variation	[477]
CALB2	OTSNMCG9	Limited	Biomarker	[888]
CAP1	OTYM8A2N	Limited	Biomarker	[531]
CARD10	OT2RPM4I	Limited	Biomarker	[889]
CAVIN1	OTFO915U	Limited	Biomarker	[890]
CBLIF	OTNE20WU	Limited	Altered Expression	[891]
CCDC33	OTOIFZ4R	Limited	Genetic Variation	[442]
CCL15	OTOGZ85M	Limited	Biomarker	[892]
CCL24	OT9LGHV0	Limited	Altered Expression	[763]
CCL28	OTY6XNQ7	Limited	Biomarker	[893]
CCL3L1	OTQXCYB1	Limited	Genetic Variation	[894]
CCL7	OTDIS99H	Limited	Altered Expression	[895]
CD151	OTF3UZS7	Limited	Biomarker	[896]
CD244	OTSMR85N	Limited	Biomarker	[897]
CD247	OT45FGUX	Limited	Genetic Variation	[486]
CD53	OT9U5OXJ	Limited	Genetic Variation	[898]
CD63	OT2UGZA9	Limited	Biomarker	[899]
CDH17	OT9EV2XK	Limited	Genetic Variation	[442]
CDHR3	OTZZ0CA8	Limited	Biomarker	[900]
CDIP1	OTKBNCPF	Limited	Biomarker	[717]
CHI3L1	OT2Z7VJH	Limited	Biomarker	[901]
CHL1	OT6E6E8P	Limited	Genetic Variation	[902]
CHST8	OTQT4TKR	Limited	Biomarker	[573]
CLEC10A	OTD8HQT6	Limited	Biomarker	[903]
CLEC11A	OT9KBH7C	Limited	Altered Expression	[904]
CLEC4E	OT7P8ICY	Limited	Altered Expression	[481]
CLEC7A	OTRTBH27	Limited	Genetic Variation	[905]
CNGB1	OTA5DE38	Limited	Genetic Variation	[681]
COG6	OTDLQITC	Limited	Genetic Variation	[486]
COL1A1	OTI31178	Limited	Altered Expression	[906]
COL4A3	OT6SB8X5	Limited	Biomarker	[907]
COL4A5	OTHG60RE	Limited	Genetic Variation	[835]
COL6A1	OTYKSCOB	Limited	Biomarker	[566]
COL6A2	OTQC6PPO	Limited	Biomarker	[566]
COL6A5	OTJT8O80	Limited	Genetic Variation	[908]
COL9A1	OTWBR27Y	Limited	Biomarker	[578]
COL9A2	OT1ZBDBV	Limited	Biomarker	[578]
COL9A3	OTCUJOEK	Limited	Biomarker	[578]
COMP	OTS2FPMI	Limited	Biomarker	[578]
CPA3	OTOK8M0V	Limited	Biomarker	[424]
CRIP1	OT0EICG3	Limited	Altered Expression	[909]
CRISPLD2	OTVSFHTL	Limited	Biomarker	[910]
CRTAM	OTXNF0NQ	Limited	Genetic Variation	[911]
CRYBG1	OTIPDI15	Limited	Biomarker	[836]
CRYGC	OTYSTQWI	Limited	Altered Expression	[717]
CTNNA1	OTFC725Z	Limited	Altered Expression	[912]
CTNNBL1	OT6KLHPA	Limited	Biomarker	[913]
CTTN	OTJRG4ES	Limited	Biomarker	[914]
CYFIP2	OTCAY35T	Limited	Biomarker	[915]
D2HGDH	OTLHXW69	Limited	Genetic Variation	[486]
DAP3	OTNPEZYM	Limited	Biomarker	[916]
DCANP1	OT99HSDU	Limited	Genetic Variation	[917]
DGKG	OTBL32T3	Limited	Biomarker	[573]
DMRT1	OT5PU9U1	Limited	Genetic Variation	[918]
DNAAF3	OT3OHO0O	Limited	Biomarker	[919]
DNAI1	OTF6C65Q	Limited	Biomarker	[919]
DNASE1L3	OTEUIMC2	Limited	Biomarker	[424]
DNER	OT2GH2E5	Limited	Biomarker	[920]
DOK7	OTR2V7HO	Limited	Genetic Variation	[921]
DPP6	OTWW3H0K	Limited	Genetic Variation	[922]
DYM	OTQ670WI	Limited	Biomarker	[923]
EAF2	OTSOET5L	Limited	Biomarker	[924]
EBNA1BP2	OTBRVMZH	Limited	Altered Expression	[526]
EEFSEC	OTJ4KKOO	Limited	Genetic Variation	[486]
EFNA1	OTU2NUA2	Limited	Altered Expression	[925]
EHF	OTY6TPWD	Limited	Genetic Variation	[926]
ELF5	OTLRU8YF	Limited	Genetic Variation	[926]
EMSY	OTBQ3KQE	Limited	Biomarker	[927]
ENTPD8	OTB9GJ1V	Limited	Altered Expression	[928]
ERO1B	OTHZ25Y8	Limited	Genetic Variation	[929]
EVI5	OTOPAP55	Limited	Genetic Variation	[467]
EXD1	OT4JCT4K	Limited	Genetic Variation	[467]
FAIM2	OT6QINVO	Limited	Biomarker	[573]
FBLN1	OT5MHHOP	Limited	Genetic Variation	[930]
FBRS	OTUVH446	Limited	Biomarker	[931]
FBXO6	OT58MKP3	Limited	Biomarker	[932]
FBXO8	OTZNGJGW	Limited	Biomarker	[933]
FHL2	OT0OAYWT	Limited	Biomarker	[934]
FHL5	OT6C00Z1	Limited	Biomarker	[412]
FLCN	OTVM78XM	Limited	Altered Expression	[935]
FLT3LG	OTU0YGC4	Limited	Biomarker	[936]
FLVCR1	OT9XCFOC	Limited	Biomarker	[937]
FOXA2	OTJOCVOY	Limited	Altered Expression	[938]
FOXP4	OTHCGIEZ	Limited	Biomarker	[939]
FRMD6	OTY6X9V5	Limited	Biomarker	[940]
FSD1	OT8P6PT3	Limited	Altered Expression	[941]
FSD1L	OTBQ48RF	Limited	Altered Expression	[941]
FZD4	OTGLZIE0	Limited	Biomarker	[490]
GADD45G	OT8V1J4M	Limited	Biomarker	[942]
GALNT17	OTMF0W2U	Limited	Genetic Variation	[943]
GFRA4	OTOLGKQM	Limited	Biomarker	[501]
GGACT	OTGPZHR9	Limited	Genetic Variation	[944]
GGTLC1	OTWJKUHQ	Limited	Genetic Variation	[945]
GIMAP4	OTEUZH06	Limited	Biomarker	[946]
GIMAP5	OTMND7IR	Limited	Genetic Variation	[947]
GLCCI1	OTU0R1CU	Limited	Genetic Variation	[948]
GLT1D1	OTXW0WXJ	Limited	Genetic Variation	[438]
GPR151	OT7EACU6	Limited	Biomarker	[490]
GREB1	OTU6ZA26	Limited	Genetic Variation	[442]
GRID1	OTJ3WIKC	Limited	Genetic Variation	[477]
GRP	OT8JDFNI	Limited	Biomarker	[949]
GSDMD	OTH39BKI	Limited	Altered Expression	[950]
GSPT1	OT18H1B0	Limited	Genetic Variation	[951]
H4C1	OTB71W46	Limited	Biomarker	[952]
HACD1	OTEC7EP7	Limited	Biomarker	[531]
HAS2	OTTD3PAL	Limited	Biomarker	[906]
HERC2	OTNQYKOB	Limited	Genetic Variation	[442]
HLA-DRA	OT7KZMP2	Limited	Biomarker	[953]
HLA-DRB3	OT5PM9N7	Limited	Genetic Variation	[486]
HLA-DRB4	OTNXIHQU	Limited	Altered Expression	[766]
HPX	OT14T7Q1	Limited	Altered Expression	[954]
HSH2D	OTOGB2BR	Limited	Biomarker	[576]
IFNA1	OTPMKY0L	Limited	Biomarker	[955]
IFNL2	OT4BMJF7	Limited	Biomarker	[956]
IFRD1	OT4SQMLQ	Limited	Biomarker	[957]
IL12RB1	OTM1IJO2	Limited	Genetic Variation	[958]
IL17RA	OTVVI8ER	Limited	Biomarker	[959]
IL1RAPL1	OTW3T4B2	Limited	Genetic Variation	[960]
IL27	OTIS3OF8	Limited	Biomarker	[510]
IL6R	OTCQL07Z	Limited	Biomarker	[961]
ILDR1	OTQK8XLK	Limited	Genetic Variation	[486]
ILVBL	OTNRRCGY	Limited	Genetic Variation	[962]
IMPACT	OTQ923OB	Limited	Biomarker	[963]
ING1	OTEZBRKW	Limited	Altered Expression	[876]
INHA	OT7HWCO3	Limited	Biomarker	[964]
INSIG2	OTX4VY51	Limited	Genetic Variation	[965]
INSRR	OT3F75WA	Limited	Biomarker	[966]
IPO13	OT887N3O	Limited	Biomarker	[967]
IRF2	OTAZRUW3	Limited	Biomarker	[506]
IRF5	OT8SIIAP	Limited	Biomarker	[968]
ISG20	OTCWRJJW	Limited	Biomarker	[480]
ITGB4	OT28UK84	Limited	Biomarker	[969]
ITLN1	OT7ZLJVV	Limited	Biomarker	[970]
ITPKA	OTX5ERUD	Limited	Genetic Variation	[486]
ITSN2	OT8S0OO8	Limited	Genetic Variation	[971]
JAKMIP1	OTEUYJIG	Limited	Genetic Variation	[438]
JAZF1	OTXTYSYD	Limited	Genetic Variation	[486]
KALRN	OT8WRCBH	Limited	Biomarker	[972]
KCNIP3	OTCQPEM4	Limited	Biomarker	[973]
KCNIP4	OTB1BS0X	Limited	Genetic Variation	[974]
KCNS3	OTHDD9F6	Limited	Biomarker	[975]
KIF16B	OTDWIFQ2	Limited	Genetic Variation	[477]
KIF3A	OTMUBSSK	Limited	Genetic Variation	[976]
KIR2DL4	OTXN18OA	Limited	Genetic Variation	[977]
KLK15	OT7BVG17	Limited	Biomarker	[978]
KLRB1	OTQ2959Y	Limited	Biomarker	[979]
KLRD1	OTMYLOV4	Limited	Genetic Variation	[977]
KLRF1	OTGHZ7FU	Limited	Altered Expression	[766]
LAMA5	OTIIXE4M	Limited	Biomarker	[980]
LELP1	OTOQIVV0	Limited	Genetic Variation	[981]
LGALS3BP	OT9AGQKH	Limited	Biomarker	[982]
LGALS9	OT7MF91K	Limited	Biomarker	[983]
LGR6	OTPZ1PWR	Limited	Biomarker	[490]
LPCAT3	OTWI96P4	Limited	Genetic Variation	[984]
LRRN2	OTGP2DCY	Limited	Biomarker	[985]
LY86	OTTZB64A	Limited	Genetic Variation	[986]
LYNX1	OTK4103B	Limited	Biomarker	[987]
MAML3	OTZFV53Z	Limited	Biomarker	[988]
MAP2K3	OTI2OREX	Limited	Biomarker	[989]
MAP6	OTPUI00F	Limited	Biomarker	[990]
MARCHF1	OTI2EYO6	Limited	Biomarker	[991]
MBD2	OTUQPP0R	Limited	Altered Expression	[992]
MDFI	OTIA6YUG	Limited	Biomarker	[993]
MED24	OTU4SJQ1	Limited	Biomarker	[994]
MLLT3	OTXH4DDG	Limited	Genetic Variation	[943]
MMP19	OTLSTT2B	Limited	Biomarker	[995]
MRGPRX3	OTRKCCDS	Limited	Biomarker	[490]
MRGPRX4	OTOBHZVA	Limited	Biomarker	[490]
MRI1	OTOP49DM	Limited	Biomarker	[996]
MROH7	OTY4H57Y	Limited	Genetic Variation	[477]
MSC	OTBRPZL5	Limited	Biomarker	[997]
MTFMT	OT1OIVJL	Limited	Biomarker	[906]
MUC19	OTM06UGV	Limited	Biomarker	[998]
MUCL3	OTGAD3I0	Limited	Genetic Variation	[999]
MYH11	OTVNVWY3	Limited	Altered Expression	[591]
MYRF	OTKF6AEB	Limited	Genetic Variation	[486]
NEGR1	OT57ECW9	Limited	Biomarker	[573]
NFATC2	OTK5T6HZ	Limited	Biomarker	[1000]
NFATC4	OTTDCUAO	Limited	Biomarker	[1001]
NFIL3	OTQH9HM3	Limited	Biomarker	[1002]
NHS	OTKE8QAT	Limited	Biomarker	[1003]
NOL3	OT1K0L0D	Limited	Biomarker	[555]
NPS	OTEG25A2	Limited	Genetic Variation	[1004]
NRROS	OT9WNOKY	Limited	Genetic Variation	[467]
NSFL1C	OTIKQF3U	Limited	Altered Expression	[876]
NUDT10	OT61XMYC	Limited	Biomarker	[960]
OAS2	OT64CCTM	Limited	Genetic Variation	[477]
OBSCN	OTT14OVX	Limited	Genetic Variation	[1005]
OR12D3	OTQ9XNBB	Limited	Genetic Variation	[442]
OR5V1	OTSYXOD6	Limited	Genetic Variation	[442]
ORM1	OTZKSBRE	Limited	Genetic Variation	[1006]
ORMDL1	OT0LBF1R	Limited	Genetic Variation	[1007]
ORMDL2	OT2N1MW0	Limited	Genetic Variation	[1007]
OTULINL	OTNOC9L1	Limited	Genetic Variation	[486]
PAFAH1B1	OT9T2TCJ	Limited	Genetic Variation	[1008]
PARD3B	OTGZ43YI	Limited	Genetic Variation	[442]
PARP14	OTFXJAKK	Limited	Biomarker	[1009]
PCBD1	OTDSRUD5	Limited	Biomarker	[919]
PEX14	OT98BZHE	Limited	Genetic Variation	[417]
PGP	OT6QQ7OR	Limited	Altered Expression	[1010]
PHF5A	OTS94JFM	Limited	Genetic Variation	[486]
PI3	OT47MTC3	Limited	Biomarker	[1011]
PIGX	OTUN0WC4	Limited	Genetic Variation	[467]
PIP5K1B	OT8JQ1F7	Limited	Biomarker	[1012]
PLEKHG4B	OTEFM296	Limited	Genetic Variation	[477]
PM20D1	OTXXNQ5K	Limited	Biomarker	[996]
PMCH	OT3D9SA4	Limited	Biomarker	[1013]
PNN	OT0HXICH	Limited	Altered Expression	[1014]
PNOC	OTJEAADN	Limited	Biomarker	[1015]
POLI	OTBA4DCE	Limited	Genetic Variation	[486]
POTEM	OT7L2HGH	Limited	Biomarker	[412]
PPIG	OTZ8BTTM	Limited	Biomarker	[1016]
PPP1R12A	OT4AVU95	Limited	Altered Expression	[1017]
PPP1R1A	OTGTAGCV	Limited	Biomarker	[1018]
PPP1R3F	OT5XRUSR	Limited	Genetic Variation	[486]
PQBP1	OTXCBEAH	Limited	Genetic Variation	[1019]
PRG2	OT0BCPQG	Limited	Biomarker	[1020]
PROCR	OTRHED17	Limited	Genetic Variation	[994]
PRORP	OTWIS44P	Limited	Genetic Variation	[438]
PRPF19	OTQ1STV3	Limited	Biomarker	[874]
PRR5L	OTQ1Z0OU	Limited	Genetic Variation	[486]
PRRT2	OTCJUBDO	Limited	Biomarker	[1021]
PRSS35	OT09H6WH	Limited	Genetic Variation	[438]
PSMA3	OT52M10V	Limited	Genetic Variation	[1022]
PSMC6	OTG8997V	Limited	Genetic Variation	[1022]
PSMD7	OT7PZZ4K	Limited	Altered Expression	[526]
PTCHD3	OTFQ1VGM	Limited	Genetic Variation	[1023]
PTPA	OTRGFOI7	Limited	Biomarker	[1024]
PTPRK	OTAP5AT3	Limited	Genetic Variation	[486]
PTTG1IP	OTX21QTE	Limited	Biomarker	[988]
RAB27A	OT9SQRWY	Limited	Altered Expression	[1025]
RAB40B	OTCA9ZF5	Limited	Biomarker	[1026]
RAB5A	OTFR2KM4	Limited	Biomarker	[1027]
RAB5B	OT06PN42	Limited	Genetic Variation	[486]
RABEPK	OTCZSREH	Limited	Altered Expression	[526]
RAG1	OTV131E4	Limited	Biomarker	[1028]
RBP7	OT0J3CPT	Limited	Altered Expression	[1029]
RERE	OT3G4GBZ	Limited	Genetic Variation	[486]
RFC2	OTJ9N6BD	Limited	Biomarker	[1030]
RGMB	OT2DROYU	Limited	Biomarker	[1031]
RIOX2	OT2YFPI2	Limited	Genetic Variation	[1032]
RIPOR2	OTXB6LIR	Limited	Genetic Variation	[442]
RPLP0	OT3XKD6Y	Limited	Altered Expression	[1033]
RPS3	OT0K3TMH	Limited	Biomarker	[1034]
RRBP1	OT4ZTPTM	Limited	Biomarker	[1035]
RSAD2	OTCA9WCM	Limited	Biomarker	[956]
RTEL1	OTI3PJCT	Limited	Genetic Variation	[486]
RTTN	OT5PB986	Limited	Genetic Variation	[902]
S100A5	OTCGGL6K	Limited	Biomarker	[566]
SAA2	OTYAVJWG	Limited	Genetic Variation	[576]
SAGE1	OT4H6FFA	Limited	Biomarker	[701]
SBNO2	OT1C6J3K	Limited	Genetic Variation	[486]
SCARB2	OTN929M8	Limited	Biomarker	[1012]
SCYL1	OTQ0IN7P	Limited	Altered Expression	[548]
SDC4	OTKUVUGZ	Limited	Altered Expression	[1036]
SDF2	OTSLRFRF	Limited	Genetic Variation	[1037]
SELENOS	OTUEWIU9	Limited	Genetic Variation	[1038]
SEMA3E	OTD4S36H	Limited	Biomarker	[1039]
SEPTIN4	OTD16B30	Limited	Biomarker	[1040]
SEPTIN8	OTSZLI64	Limited	Genetic Variation	[486]
SERBP1	OTZVSU0X	Limited	Genetic Variation	[1041]
SERPINA3	OT9BP2S0	Limited	Biomarker	[412]
SERPINB6	OT7G55IK	Limited	Biomarker	[531]
SERPINB7	OTZ95LR2	Limited	Genetic Variation	[486]
SERPINE2	OTYF5340	Limited	Biomarker	[825]
SERPINF2	OTZGAF8B	Limited	Biomarker	[1042]
SETBP1	OTKGCOSR	Limited	Genetic Variation	[1043]
SFSWAP	OT7H3ETA	Limited	Genetic Variation	[1044]
SFTPA2	OT6SFOMU	Limited	Genetic Variation	[1045]
SFTPC	OTIZJD09	Limited	Biomarker	[1046]
SH2B1	OTJZO2CI	Limited	Biomarker	[881]
SH3PXD2A	OTYRQJIH	Limited	Genetic Variation	[442]
SIGLEC1	OTNWSQA9	Limited	Biomarker	[501]
SIRT7	OT5M4OT4	Limited	Biomarker	[1047]
SLURP1	OT89YD2E	Limited	Altered Expression	[1048]
SMN2	OT54RLO1	Limited	Altered Expression	[588]
SOCS5	OTN1ABYR	Limited	Genetic Variation	[1049]
SOD3	OTIOZQAB	Limited	Genetic Variation	[1050]
SORBS1	OTWH8762	Limited	Biomarker	[531]
SPATS2L	OTFO07H8	Limited	Biomarker	[1051]
SPEN	OT37A2MD	Limited	Biomarker	[974]
SPSB1	OTGY26U4	Limited	Genetic Variation	[486]
SRA1	OTYOGMTG	Limited	Biomarker	[545]
ST13	OTNML6UP	Limited	Genetic Variation	[1052]
STAT2	OTO9G2RZ	Limited	Genetic Variation	[1053]
STATH	OTQHBHM9	Limited	Biomarker	[461]
STIP1	OT7TXLOX	Limited	Genetic Variation	[1054]
SYNPO2	OTC3U0YH	Limited	Genetic Variation	[554]
TAAR6	OTUBUJ2N	Limited	Genetic Variation	[1055]
TAB1	OTPM6F85	Limited	Biomarker	[1056]
TAC1	OTM842YW	Limited	Altered Expression	[1057]
TAC3	OTOJGM38	Limited	Biomarker	[1058]
TAC4	OTYWPPM3	Limited	Biomarker	[544]
TADA1	OTV9RKSL	Limited	Biomarker	[866]
TADA2A	OTXUMEL9	Limited	Biomarker	[866]
TAPBP	OTL81AVZ	Limited	Genetic Variation	[1059]
TAS2R10	OT4RWZZD	Limited	Genetic Variation	[1060]
TAS2R14	OTWA9CYC	Limited	Biomarker	[1061]
TATDN1	OTQ3S9AL	Limited	Genetic Variation	[508]
TBCD	OTS4JKNQ	Limited	Genetic Variation	[922]
TCF7	OT1ID822	Limited	Biomarker	[1062]
TDRKH	OTV21BN1	Limited	Genetic Variation	[486]
TENM3	OTWY13GR	Limited	Genetic Variation	[442]
TESPA1	OTEGT4GI	Limited	Genetic Variation	[486]
TET1	OTZDHT1D	Limited	Biomarker	[1063]
TFF2	OTRXB19X	Limited	Genetic Variation	[831]
TJP1	OTBDCUPK	Limited	Altered Expression	[912]
TLE4	OT4QEH6T	Limited	Biomarker	[1064]
TM7SF2	OTILU5S7	Limited	Biomarker	[540]
TMEM18	OT05YQ1E	Limited	Genetic Variation	[541]
TMEM258	OTXSDU14	Limited	Genetic Variation	[486]
TNFAIP8L2	OTII0RM0	Limited	Biomarker	[475]
TOLLIP	OTYEO4NR	Limited	Altered Expression	[1065]
TRAF2	OT1MEZZN	Limited	Altered Expression	[1066]
TSC22D3	OT03UM03	Limited	Altered Expression	[1067]
TSFM	OTP6OKPJ	Limited	Genetic Variation	[1068]
ARHGEF1	OTXU4HBW	Disputed	Altered Expression	[1069]
CCL8	OTCTWYN8	Disputed	Altered Expression	[950]
CD93	OT6HZT6H	Disputed	Biomarker	[1070]
CORT	OTX3GUHB	Disputed	Posttranslational Modification	[1071]
CST2	OTRKRW50	Disputed	Altered Expression	[1072]
CXCL17	OTRCEVIZ	Disputed	Biomarker	[1073]
DACT1	OT19Z704	Disputed	Altered Expression	[1074]
DACT2	OTNLCC0K	Disputed	Altered Expression	[1074]
DACT3	OTSNQ55G	Disputed	Altered Expression	[1074]
DGKB	OTTT9SZJ	Disputed	Biomarker	[1075]
DGKE	OTWS86AS	Disputed	Biomarker	[1075]
DGUOK	OT78HUZB	Disputed	Biomarker	[1075]
EFEMP2	OT0I2B4J	Disputed	Biomarker	[1020]
GPRASP1	OTPYQYUD	Disputed	Biomarker	[1076]
HIVEP1	OT7CAG4A	Disputed	Biomarker	[1020]
ITGA7	OTTBTAYW	Disputed	Altered Expression	[1077]
LAMA4	OTHI7TA0	Disputed	Biomarker	[980]
LBR	OT1HG3HG	Disputed	Biomarker	[1078]
MLKL	OTDSLC81	Disputed	Biomarker	[1079]
MRGPRF	OT74OZ2Z	Disputed	Biomarker	[1080]
NIBAN1	OTYOLI12	Disputed	Biomarker	[1081]
PIGR	OT6GLSUL	Disputed	Altered Expression	[1082]
RBFOX2	OTXY1WVH	Disputed	Biomarker	[1080]
THSD7A	OT7249HH	Disputed	Genetic Variation	[1083]
TMEM178A	OTQZY4NP	Disputed	Biomarker	[1084]
TRAT1	OTMPUNPD	Disputed	Biomarker	[622]
ACSL3	OT3MWER1	moderate	Biomarker	[1085]
ADAMTS12	OTG7HEA2	moderate	Biomarker	[1086]
AKAP6	OTN59BZS	moderate	Genetic Variation	[1087]
ALLC	OTZE4XV7	moderate	Biomarker	[1088]
ARHGAP31	OTUYTF4I	moderate	Genetic Variation	[647]
ASXL3	OTNDJWEZ	moderate	CausalMutation	[1089]
ATF6	OTAFHAVI	moderate	Altered Expression	[1090]
ATG16L1	OTEOYC5D	moderate	Genetic Variation	[647]
ATG5	OT4T5SMS	moderate	Altered Expression	[1091]
CCDC167	OTUIAUE7	moderate	Genetic Variation	[442]
CCHCR1	OT22C116	moderate	Genetic Variation	[1092]
CCL1	OT23NON8	moderate	Biomarker	[1093]
CCL19	OTQ2UJMH	moderate	Biomarker	[631]
CD48	OT83ZNPP	moderate	Biomarker	[1094]
CDC42	OT5QBC5M	moderate	Biomarker	[1095]
CDKAL1	OTA0SGNE	moderate	Genetic Variation	[647]
CDSN	OTQW4HV6	moderate	Genetic Variation	[477]
CEP68	OTZDM4J1	moderate	Genetic Variation	[1096]
CKAP4	OTDUC9ME	moderate	Altered Expression	[1097]
CKLF	OTHLPHA0	moderate	Biomarker	[1098]
CLC	OTYMYR85	moderate	Biomarker	[424]
CLEC16A	OTLGV5SV	moderate	Genetic Variation	[486]
CLOCK	OTNEOJY7	moderate	Altered Expression	[1099]
CLSTN1	OTQN35G2	moderate	Genetic Variation	[442]
CMYA5	OTYV0RME	moderate	Genetic Variation	[442]
COMMD10	OT1ANQLQ	moderate	Biomarker	[1100]
COX1	OTG3O9BN	moderate	Altered Expression	[1101]
COX5A	OTP0961M	moderate	Altered Expression	[1102]
COX8A	OTU0NR39	moderate	Altered Expression	[1102]
CPOX	OTIAY121	moderate	Altered Expression	[1102]
CRB1	OTXYUNG0	moderate	Genetic Variation	[1103]
CRIM1	OTTZNV6Y	moderate	Genetic Variation	[554]
CSMD1	OTIVDSC4	moderate	Genetic Variation	[689]
CST4	OTXXM8EH	moderate	Altered Expression	[809]
CYLD	OT37FKH0	moderate	Genetic Variation	[536]
DDX1	OT3U8FD0	moderate	Biomarker	[1100]
DDX39B	OTEVCFVU	moderate	Genetic Variation	[661]
DGKH	OTYNPJ4B	moderate	Genetic Variation	[1104]
DNAH5	OTC21RUS	moderate	Biomarker	[919]
DPH1	OT0QU3JY	moderate	Genetic Variation	[442]
ELP1	OTYEWBF7	moderate	Biomarker	[1105]
FAM13A	OTZ6GN0Q	moderate	Biomarker	[1106]
FBXL7	OTNUK1DJ	moderate	Biomarker	[705]
FLAD1	OTY8R02L	moderate	Altered Expression	[669]
FLNC	OT3F8J6Y	moderate	Biomarker	[1107]
FSTL1	OT6KEZUD	moderate	Altered Expression	[1108]
GATA1	OTX1R7O1	moderate	Altered Expression	[1109]
GCNA	OTIU3F9Y	moderate	Biomarker	[1110]
HLA-DPA1	OT7OG7Y2	moderate	Genetic Variation	[687]
HLA-DRB5	OTUX5TWM	moderate	Genetic Variation	[486]
HLX	OT7DTH46	moderate	Genetic Variation	[1111]
IKZF4	OTHGPHOM	moderate	Genetic Variation	[637]
IRGM	OTKD3O5Z	moderate	Genetic Variation	[647]
KAT5	OTL7257A	moderate	Biomarker	[789]
KCNE4	OTNYW0OL	moderate	Genetic Variation	[661]
KIDINS220	OTLBH2MA	moderate	Altered Expression	[1112]
KRT7	OTLT3JFN	moderate	Genetic Variation	[442]
KRT81	OTMKIK2S	moderate	Genetic Variation	[442]
LACC1	OT4SBHI8	moderate	Genetic Variation	[647]
LPIN2	OTRRTMXX	moderate	Genetic Variation	[1113]
LPP	OT6TU8SE	moderate	Genetic Variation	[486]
LRP2BP	OTVEH7V5	moderate	Genetic Variation	[639]
LUC7L2	OTOP9Q1V	moderate	Genetic Variation	[442]
MFAP1	OTZN4FT3	moderate	Biomarker	[1114]
MOK	OTQK7M9V	moderate	Biomarker	[1115]
MPP7	OT3G3HTZ	moderate	Genetic Variation	[442]
MS4A3	OT0CEJOO	moderate	Genetic Variation	[1116]
MST1	OTOC4UNG	moderate	Genetic Variation	[647]
MUC2	OT3X4QVX	moderate	Biomarker	[1117]
NDFIP1	OTIORSWF	moderate	Genetic Variation	[486]
NEDD4L	OT1B19RU	moderate	Genetic Variation	[1118]
NEUROD1	OTZQ7QJ2	moderate	Genetic Variation	[1119]
OPN3	OTON6BFU	moderate	Biomarker	[1120]
OTOG	OT5U4SVN	moderate	Genetic Variation	[442]
PDZRN4	OTHPD5LB	moderate	Genetic Variation	[442]
PHF19	OTF6RUCR	moderate	Genetic Variation	[681]
PITPNC1	OT64TTGC	moderate	Genetic Variation	[442]
PLEK	OTB73XXA	moderate	Altered Expression	[876]
PPP1R12B	OTONIS87	moderate	Genetic Variation	[661]
PRICKLE2	OTWBA48T	moderate	Genetic Variation	[442]
PSORS1C1	OT9HK436	moderate	Genetic Variation	[477]
PTCH1	OTMG07H5	moderate	Biomarker	[1121]
PTPN22	OTDCNTC3	moderate	Genetic Variation	[1122]
PTPRD	OTZPJ3GX	moderate	Biomarker	[573]
PTPRE	OTOD5NID	moderate	Genetic Variation	[1123]
PUS10	OTFFJWZX	moderate	Genetic Variation	[647]
PYHIN1	OT30GD05	moderate	Biomarker	[1124]
RAD51B	OTCJVRMY	moderate	Genetic Variation	[486]
RAPGEF6	OTR1QQA3	moderate	Genetic Variation	[442]
RAPSN	OTGMSWDQ	moderate	Altered Expression	[669]
RASGRP4	OT15PWN4	moderate	Biomarker	[1125]
RETNLB	OT9JJQQQ	moderate	Biomarker	[1126]
RGS22	OTCTFGW6	moderate	Genetic Variation	[645]
RMI2	OTA0HP4S	moderate	Genetic Variation	[647]
SAXO1	OT7M6PLA	moderate	Genetic Variation	[442]
SIGIRR	OTNC3XFD	moderate	Biomarker	[1127]
SIGLEC14	OT2JGGXD	moderate	Biomarker	[1128]
SNRNP70	OTP52YZ3	moderate	Genetic Variation	[1129]
SRP9	OT4CQTCM	moderate	Genetic Variation	[645]
STK10	OTC33Y2F	moderate	Genetic Variation	[1130]
TAGAP	OTHJNNO2	moderate	Genetic Variation	[647]
TAP2	OTWSYFI7	moderate	Genetic Variation	[681]
TBX1	OTQLBPRA	moderate	Biomarker	[1131]
TMEM26	OTHZCXYB	moderate	Genetic Variation	[442]
TPR	OTUBBA4W	moderate	Biomarker	[698]
TSBP1	OT5GE8IO	moderate	Genetic Variation	[637]
ACP1	OTJ9CKLU	Strong	Genetic Variation	[795]
ARHGEF28	OT3F32IU	Strong	Altered Expression	[798]
ARIH1	OTO3XDR2	Strong	Biomarker	[1132]
ATP5F1A	OT3FZDLX	Strong	Genetic Variation	[1006]
B3GAT1	OTXFP98E	Strong	Biomarker	[721]
BATF	OT9VSD2D	Strong	Altered Expression	[722]
BGLAP	OTK1YLWQ	Strong	Biomarker	[1133]
BST1	OTAV5SE7	Strong	Genetic Variation	[1134]
C4A	OTXMOYXU	Strong	Altered Expression	[1135]
C6	OTCKR304	Strong	Genetic Variation	[1136]
CA10	OTC3N1F6	Strong	Biomarker	[1137]
CACNG6	OT2PC1E1	Strong	Genetic Variation	[1138]
CALU	OTSYQN71	Strong	Altered Expression	[1139]
CAMK4	OT47RDGV	Strong	Genetic Variation	[746]
CCL13	OTNX0JD0	Strong	Altered Expression	[903]
CCL18	OT7JYSK9	Strong	Altered Expression	[1140]
CCL26	OT2B7HR9	Strong	Altered Expression	[1141]
CCL27	OTUZYC61	Strong	Biomarker	[1142]
CD1D	OT3ROU4J	Strong	Biomarker	[608]
CDC42EP4	OTCPHZGJ	Strong	Biomarker	[1143]
CETN1	OTGQ8JOZ	Strong	Biomarker	[1144]
CIB2	OT9ZJX1I	Strong	Biomarker	[1145]
CIITA	OTRJNZFO	Strong	Biomarker	[1146]
COL26A1	OTMS7RNF	Strong	Genetic Variation	[1147]
CRNN	OTAORBR4	Strong	Genetic Variation	[1148]
CSTA	OT1K68KE	Strong	Genetic Variation	[1149]
CTNNA3	OT9Z0P1E	Strong	Biomarker	[1150]
CXCL14	OTM189TA	Strong	Biomarker	[647]
CYBA	OT16N9ZO	Strong	Biomarker	[1151]
DAD1	OTUUNQBT	Strong	Biomarker	[1152]
DBNL	OTT2OQOV	Strong	Genetic Variation	[706]
DCBLD2	OTB71I02	Strong	Genetic Variation	[1153]
DEFB1	OT5SV0E4	Strong	Biomarker	[1154]
DENND1B	OT3VCNPE	Strong	Biomarker	[1155]
DEXI	OT60W9CN	Strong	Genetic Variation	[773]
DNAH11	OT6IYFVV	Strong	Genetic Variation	[1156]
DOCK5	OT63I0CL	Strong	Biomarker	[1143]
DOCK8	OTNQLL21	Strong	Biomarker	[1157]
DTD1	OT63V2KK	Strong	Genetic Variation	[1158]
ECSCR	OT9L72MD	Strong	Biomarker	[552]
EFHC1	OTS9IBNE	Strong	Genetic Variation	[800]
FAM167A	OT9JF3JQ	Strong	Biomarker	[711]
FANCC	OTTIDM3P	Strong	Genetic Variation	[1159]
FBXL20	OTVTR1KY	Strong	Genetic Variation	[746]
FCER1A	OTIRUOHF	Strong	Genetic Variation	[1160]
FCRL3	OTIFXFWL	Strong	Genetic Variation	[1161]
FCRL5	OTA7VHNE	Strong	Genetic Variation	[1161]
FGA	OTMIHY80	Strong	Therapeutic	[744]
FMR1	OTWEV0T5	Strong	Biomarker	[1162]
FOSB	OTW6C05J	Strong	Biomarker	[749]
FOXJ1	OT7LLBZ7	Strong	Altered Expression	[1163]
FSIP1	OTYLL6GM	Strong	Genetic Variation	[1164]
GC	OTWS63BY	Strong	Genetic Variation	[1165]
GPR42	OTEB0ROY	Strong	Biomarker	[411]
GPR65	OTCF5O4G	Strong	Altered Expression	[1166]
GSTM2	OTG4WT05	Strong	Biomarker	[1167]
GSTT2B	OTCMRDLE	Strong	Genetic Variation	[1168]
HAVCR2	OTOL603T	Strong	Altered Expression	[1169]
HLA-DPB1	OTW8JHU2	Strong	Biomarker	[1170]
HLA-DQA2	OT1DH0N9	Strong	Genetic Variation	[746]
HOXD13	OTWSC8TF	Strong	Altered Expression	[1171]
HSPA4	OT5HR0AR	Strong	Biomarker	[714]
HSPB6	OTFPLGZI	Strong	Biomarker	[1172]
IFIH1	OTZA2AHA	Strong	Genetic Variation	[1173]
IGFBP4	OT2HZRBD	Strong	Altered Expression	[1174]
IL17RB	OT0KDNSF	Strong	Biomarker	[959]
IL18BP	OTW0LRYZ	Strong	Altered Expression	[1175]
IL18R1	OT83XMPQ	Strong	Genetic Variation	[486]
IL1F10	OTJAASGC	Strong	Biomarker	[1176]
IL20RA	OTSIVBVS	Strong	Biomarker	[759]
IL27RA	OTSQBAKI	Strong	Genetic Variation	[1177]
IL9R	OTILCLXA	Strong	Biomarker	[1178]
IRF4	OT1DHQ1P	Strong	Genetic Variation	[486]
IRF7	OTC1A2PQ	Strong	Altered Expression	[1179]
ISYNA1	OT49ONSE	Strong	Altered Expression	[1180]
ITGAX	OTOGIMHE	Strong	Altered Expression	[579]
JAG1	OT3LGT6K	Strong	Biomarker	[524]
JUNB	OTG2JXV5	Strong	Biomarker	[749]
JUND	OTNKACJD	Strong	Biomarker	[749]
KCNMB1	OTO4KNJ4	Strong	Genetic Variation	[1181]
KLK11	OT5PKX7Y	Strong	Biomarker	[1182]
LAMA1	OTQZMP86	Strong	Biomarker	[1183]
LAT	OTZC1XZ1	Strong	Biomarker	[791]
LRBA	OTOUZN9G	Strong	Biomarker	[1184]
LRPPRC	OTXSK5LP	Strong	Biomarker	[1185]
LZTR1	OTIDM6XO	Strong	CausalMutation	[1186]
MCC	OTQVI1EM	Strong	Genetic Variation	[1187]
MED1	OTOO24C4	Strong	Genetic Variation	[746]
MICB	OTS2DVDW	Strong	Genetic Variation	[746]
MID1	OTWN1PGU	Strong	Biomarker	[1024]
MMRN1	OT7ZNYHT	Strong	Biomarker	[937]
MS4A2	OTMCAS2D	Strong	Biomarker	[1188]
MUC5B	OTPW6K5C	Strong	Biomarker	[1189]
MYDGF	OT9HRPL6	Strong	Biomarker	[1190]
MZF1	OTMVZCPW	Strong	Genetic Variation	[1191]
NBR1	OTVRL7J9	Strong	Biomarker	[1192]
NFIA	OTDHQ9CG	Strong	Biomarker	[1193]
NUFIP2	OTZBZ224	Strong	Genetic Variation	[1162]
OVOL1	OTFJ62UI	Strong	Genetic Variation	[746]
OXA1L	OTS0BFRD	Strong	Biomarker	[1152]
PAMR1	OT83ZH5U	Strong	Biomarker	[736]
PBX2	OTEBYCAW	Strong	Biomarker	[1194]
PDIA3	OTHPQ0Q3	Strong	Biomarker	[1195]
PEX5	OTK4LMG7	Strong	CausalMutation	[1196]
PHF11	OT5F6LUP	Strong	Biomarker	[1197]
PKDCC	OTVXJR26	Strong	Genetic Variation	[1137]
PLA2G10	OTRZ2L5A	Strong	Biomarker	[1198]
POM121L2	OTQI36MZ	Strong	Genetic Variation	[746]
PPBP	OT1FHGQS	Strong	Altered Expression	[1199]
PRF1	OTFVXD7H	Strong	Biomarker	[1200]
PRMT2	OT63JZCI	Strong	Biomarker	[715]
PSMD3	OT585WY8	Strong	Genetic Variation	[746]
RAB1A	OTKPHRD0	Strong	Biomarker	[1201]
RAMP1	OT7UT2XB	Strong	Biomarker	[736]
RASGRF1	OTNWJ7EN	Strong	Biomarker	[1202]
RCC1	OT25AGMB	Strong	Biomarker	[1202]
RGS7BP	OTAGSWMH	Strong	Genetic Variation	[1203]
RNASE2	OT8Z4FNE	Strong	Altered Expression	[1204]
RNASE3	OTVE2XD1	Strong	Altered Expression	[763]
RNF111	OTO3QT6Q	Strong	Biomarker	[1205]
RPS20	OTI8052R	Strong	Biomarker	[1206]
RPTN	OTOAA25U	Strong	Genetic Variation	[1148]
RYR2	OT0PF19E	Strong	Genetic Variation	[1207]
SCGB1C1	OTA137WF	Strong	Genetic Variation	[1208]
SDF4	OTQ7WFYW	Strong	Biomarker	[1144]
SEC14L3	OTGQ8GWM	Strong	Altered Expression	[730]
SEMA4A	OT8901H3	Strong	Biomarker	[1209]
SERPINB2	OT72QLZB	Strong	Altered Expression	[809]
SFTPA1	OT87XL1U	Strong	Biomarker	[1210]
SFTPB	OTOHS07E	Strong	Biomarker	[1211]
SIGLEC8	OTQ5TRRV	Strong	Genetic Variation	[724]
SIGLEC9	OTZC7SIM	Strong	Biomarker	[1212]
SMAD2	OTC6VB4K	Strong	Altered Expression	[937]
SMAP2	OTPGVRKO	Strong	Genetic Variation	[1213]
SOSTDC1	OTAKDNSM	Strong	Biomarker	[1214]
SPAG11A	OTNQ9UB0	Strong	Genetic Variation	[1215]
SPATA32	OTBHG2TR	Strong	Genetic Variation	[746]
SPRR2B	OTQ9WPKY	Strong	Genetic Variation	[1216]
STX1B	OTSW59X0	Strong	Biomarker	[1217]
TAB2	OTPZK76F	Strong	Biomarker	[1218]
TGFBR3	OTQOOUC4	Strong	Biomarker	[1219]
THBS2	OTXET551	Strong	Biomarker	[1220]
TIMD4	OTGGC20G	Strong	Biomarker	[1221]
TIMP3	OTDGQAD1	Strong	Biomarker	[1222]
TMEM196	OTPFLB1R	Strong	Genetic Variation	[1223]
TMTC2	OTY1QWYU	Strong	Genetic Variation	[800]
TNFAIP8	OT1G9297	Strong	Genetic Variation	[746]
TNIP1	OTRAOTEW	Strong	Biomarker	[1224]
TNS1	OTZ8S1PL	Strong	Genetic Variation	[773]
TPI1	OT14KP4B	Strong	Genetic Variation	[1221]
TRIM26	OTS0DJIP	Strong	Genetic Variation	[1225]
ABCA13	OTTHTUQN	Definitive	Biomarker	[816]
ADCY10	OTYSTB0R	Definitive	Biomarker	[1226]
ALDH3A1	OTAYZZE6	Definitive	Biomarker	[1227]
AMELX	OTIN26MM	Definitive	Biomarker	[1228]
ANKRD42	OTYDDJ64	Definitive	Biomarker	[1229]
AP5B1	OTZGM9QA	Definitive	Biomarker	[516]
APOBEC3B	OTHLNI51	Definitive	Biomarker	[1230]
APOBEC3C	OTPL0AI1	Definitive	Biomarker	[1230]
CCR10	OT7ZWSSD	Definitive	Biomarker	[1231]
CPSF4	OT53UK5L	Definitive	Genetic Variation	[1232]
CST1	OTE4I83Q	Definitive	Altered Expression	[1233]
CTNND2	OTYKE30Y	Definitive	Altered Expression	[1234]
CXCL16	OTD49T9R	Definitive	Biomarker	[1235]
EFHD2	OTM9VMN3	Definitive	Biomarker	[1236]
EIF1	OTB4GZ0V	Definitive	Altered Expression	[830]
ELOA	OTOQTF5K	Definitive	Biomarker	[1237]
ELOB	OTZ3X84T	Definitive	Biomarker	[1237]
ELOC	OT0XHHWP	Definitive	Biomarker	[1237]
EMP1	OTSZHUHQ	Definitive	Genetic Variation	[1238]
ESPL1	OTMGEVOK	Definitive	Biomarker	[1239]
GAB1	OTQKE6V4	Definitive	Biomarker	[1240]
GSDMB	OTWA7P10	Definitive	Genetic Variation	[486]
KNTC1	OTI2OOFN	Definitive	Biomarker	[1241]
LGALS7	OTMSVI7R	Definitive	Biomarker	[1242]
LSM2	OTHL77NY	Definitive	Biomarker	[1243]
MARCHF3	OT89V4N5	Definitive	Biomarker	[1244]
MOXD1	OTUMCWRN	Definitive	Altered Expression	[848]
MRPL44	OT27ZC26	Definitive	Biomarker	[825]
MYH15	OTWZA8IF	Definitive	Genetic Variation	[1245]
NLRP4	OT864X7M	Definitive	Biomarker	[1246]
PHEX	OTG7N3J7	Definitive	Biomarker	[1247]
SCGB3A1	OTIR98RB	Definitive	Genetic Variation	[1248]
SCGB3A2	OTB63PHR	Definitive	Genetic Variation	[1249]
SERPINB10	OT5ZM0X6	Definitive	Altered Expression	[1141]
SERPINB4	OT88LHZ8	Definitive	Biomarker	[828]
SKP1	OT5BPAZ4	Definitive	Biomarker	[1237]
SOX17	OT9H4WWE	Definitive	Biomarker	[1250]
ST6GAL1	OT7US3NO	Definitive	Biomarker	[1251]
TBPL1	OT4I143E	Definitive	Altered Expression	[549]
THEMIS	OTXODBXJ	Definitive	Biomarker	[1076]
TIMMDC1	OTIK4I5R	Definitive	Altered Expression	[1062]

References

• [1] Adenosine receptors: development of selective agonists and antagonists. Prog Clin Biol Res. 1987;230:41-63.
• [2] ClinicalTrials.gov (NCT02491970) Study to Evaluate Small Airway Parameters of Fluticasone/Formoterol (Flutiform) Compared to Fluticasone/Salmeterol in Asthma Patients.
• [3] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6601).
• [4] Wilson and Gisvold's textbook of organic medicinal and pharmaceutical chemistry. 2004, P353. By Charles Owens Wilson, John H. Block, Ole Gisvold, John Marlowe Beale.
• [5] 2017 FDA drug approvals.Nat Rev Drug Discov. 2018 Feb;17(2):81-85.
• [6] Betamethasone FDA Label
• [7] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
• [8] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7540).
• [9] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7434).
• [10] FDA Approved Drug Products from FDA Official Website. 2019. Application Number: (NDA) 202129
• [11] Prolonged protection against exercise-induced bronchoconstriction by the leukotriene D4-receptor antagonist cinalukast. J Allergy Clin Immunol. 1997 Feb;99(2):210-5.
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• [13] Cardiovascular and adenylate cyclase stimulating effects of colforsin daropate, a water-soluble forskolin derivative, compared with those of isoproterenol, dopamine and dobutamine. Circ J. 2002 Dec;66(12):1150-4.
• [14] Cortisone acetate FDA Label
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• [16] Desonide FDA Label
• [17] Dexamethasone FDA Label
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• [19] Dyphylline FDA Label
• [20] Effects of enprofylline, a new xanthine derivate, on human pregnant myometrium. Am J Obstet Gynecol. 1987 Apr;156(4):958-62.
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• [22] Epinephrine FDA Label
• [23] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 557).
• [24] Flunisolide FDA Label
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• [26] Radium 223 dichloride for prostate cancer treatment. Drug Des Devel Ther. 2017 Sep 6;11:2643-2651.
• [27] ClinicalTrials.gov (NCT00539006) Comparator Study Evaluating Patient Preference Of FFNS vs. FPNS. U.S. National Institutes of Health.
• [28] Hydrocortisone FDA Label
• [29] Repurposing ibudilast to mitigate Alzheimer's disease by targeting inflammation. Brain. 2023 Mar 1;146(3):898-911.
• [30] ClinicalTrials.gov (NCT00442351) Efficacy and Tolerability of Maintenance Treatment With Asmanex Twisthaler Versus Placebo in Mild/Moderate Persistent Asthmatics (Study P04654)(TERMINATED). U.S. National Institutes of Health.
• [31] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5004).
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