Details of the Drug

General Information of Drug (ID: DMBTVFE)

Drug Name
MEDI-551
Indication
Disease Entry ICD 11 Status REF
Encephalopathy 8E47 Phase 2 [1]
Neuromyelitis optica 8A43 Phase 2 [1]
Chronic lymphocytic leukaemia 2A82.0 Phase 1 [2]
Drug Type
Antibody
Cross-matching ID
TTD ID
D0R3ZE
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
B-lymphocyte surface antigen B4 (CD19) TTW640A CD19_HUMAN Not Available [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Encephalopathy
ICD Disease Classification 8E47
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
B-lymphocyte surface antigen B4 (CD19) DTT CD19 2.33E-24 -1.06 -1.33
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7992).
3 Clinical pipeline report, company report or official report of MedImmune (2011).