Details of the Drug

General Information of Drug (ID: DMBUAC6)

Drug Name

GSK4532990

Indication

Disease Entry	ICD 11	Status	REF
Non-alcoholic steatohepatitis	DB92.1	Phase 2	[1]
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Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
17-beta-hydroxysteroid dehydrogenase 13 (HSD17B13)	TTDJYZR	DHB13_HUMAN	Silencer	[2]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT05583344) 17 beta-Hydroxysteroid Dehydrogenase Type 13 Minimization for the Treatment of NASH (HORIZON): A Double-Blind, Placebo-Controlled Phase 2b Study to Evaluate the Efficacy and Safety of GSK4532990 in Adults With Pre-Cirrhotic Nonalcoholic Steatohepatitis. U.S.National Institutes of Health.
2	Clinical pipeline report, company report or official report of Arrowhead Pharmaceuticals