Details of the Drug

General Information of Drug (ID: DMC8NAO)

Drug Name

ADXS-HPV

Indication

Disease Entry	ICD 11	Status	REF
Cervical cancer	2C77.0	Phase 2	[1]
Cervical Intraepithelial neoplasia	2E66.1	Phase 2	[1]
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Drug Type

Vaccine

Cross-matching ID

Repurposed Drugs (RPD)

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Human papillomavirus protein E7 (HPV E7)	TT3CPZW	VE7_HPV16	Not Available	[2]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT02002182) Window of Opportunity Trial of ADXS 11-001 Vaccination Prior to Robotic Surgery of HPV-Positive Oropharyngeal Cancer. U.S. National Institutes of Health.
2	ADXS11-001 immunotherapy targeting HPV-E7: updated survival and safety data from a phase 2 study in Indian women with recurrent/refractory cervical cancer. Journal for ImmunoTherapy of Cancer, 2013, 1(Suppl 1):P231.