General Information of Drug (ID: DMCERAB)

Drug Name
Sudapyridine
Synonyms
Sudapyridine; WX-081; 1859978-72-5; 7X86XPE5TG; GTPL13002; GLXC-25909; HY-146158; CS-0527337; (1R,2S)-1-[5-(4-chlorophenyl)-2-methoxypyridin-3-yl]-4-(dimethylamino)-2-naphthalen-1-yl-1-phenylbutan-2-ol; (alphaS,betaR)-5-(4-Chlorophenyl)-alpha-[2-(dimethylamino)ethyl]-2-methoxy-alpha-1-naphthalenyl-beta-phenyl-3-pyridineethanol; 3-Pyridineethanol, 5-(4-chlorophenyl)-alpha-[2-(dimethylamino)ethyl]-2-methoxy-alpha-1-naphthalenyl-beta-phenyl-, (alphaS,betaR)-
Indication
Disease Entry ICD 11 Status REF
Tuberculosis 1B10-1B14 Phase 3 [1]
Drug Type
Small molecule
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C34H33ClN2O2
Canonical SMILES
CN(C)CCC(C1=CC=CC2=CC=CC=C21)(C(C3=CC=CC=C3)C4=C(N=CC(=C4)C5=CC=C(C=C5)Cl)OC)O
InChI
InChI=1S/C34H33ClN2O2/c1-37(2)21-20-34(38,31-15-9-13-25-10-7-8-14-29(25)31)32(26-11-5-4-6-12-26)30-22-27(23-36-33(30)39-3)24-16-18-28(35)19-17-24/h4-19,22-23,32,38H,20-21H2,1-3H3/t32-,34-/m1/s1
InChIKey
MMUCHWPQRGEHDV-ZFEZZJPFSA-N
Cross-matching ID
PubChem CID
156777270
TTD ID
D3TW7I

References

1 ClinicalTrials.gov (NCT05824871) A Multicenter, Randomized, Double-blind, Positive Control Study to Evaluate the Efficacy and Safety of Sudapyridine (WX-081) Tables in Patients With Rifampicin-resistant Pulmonary Tuberculosis. U.S.National Institutes of Health.