Details of the Drug

General Information of Drug (ID: DMCNAME)

Drug Name
DACTHF
Synonyms Deazaacyclotetrahydrofolate; 5-deazaacyclotetrahydrofolate; 5-DACTHF
Cross-matching ID
INTEDE ID
DR0019

Molecular Interaction Atlas of This Drug


Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Folylpolyglutamate synthase (FPGS)
Main DME 		DECWT2V FOLC_HUMAN Substrate [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Role of folylpolyglutamate synthetase in the metabolism and cytotoxicity of 5-deazaacyclotetrahydrofolate, an anti-purine drug. J Biol Chem. 1994 Apr 1;269(13):9714-20.