Details of the Drug

General Information of Drug (ID: DMCSLZ4)

Drug Name

Sodium zirconium cyclosilicate

Synonyms

UZSi 9; ZS-9 compound; Sodium zirconium silicate (Na2ZrSi3O9); UZSi-9; CBTCHTJSGLCFMY-UHFFFAOYSA-N; 543686-27-7

Indication

Disease Entry	ICD 11	Status	REF
Hyperkalemia	5C76	Approved	[1]
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Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski):
1

Molecular Weight

371.5

Logarithm of the Partition Coefficient

Not Available

Rotatable Bond Count

0

Hydrogen Bond Donor Count

6

Hydrogen Bond Acceptor Count

9

Chemical Identifiers

Formula: H6Na2O9Si3Zr+2
IUPAC Name: disodium;2,2,4,4,6,6-hexahydroxy-1,3,5,2,4,6-trioxatrisilinane;zirconium
Canonical SMILES: O[Si]1(O[Si](O[Si](O1)(O)O)(O)O)O.[Na+].[Na+].[Zr]
InChI: InChI=1S/2Na.H6O9Si3.Zr/c;;1-10(2)7-11(3,4)9-12(5,6)8-10;/h;;1-6H;/q2*+1;;
InChIKey: CBTCHTJSGLCFMY-UHFFFAOYSA-N

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	2018 FDA drug approvals.Nat Rev Drug Discov. 2019 Feb;18(2):85-89.