Details of Disease

General Information of Disease (ID: DIS1KZD2)

• Disease Name: Hyperkalemia
• Disease Class: 5C76: Hyperkalaemia
• Disease Hierarchy:
  DIS01GPL: Grass pollen hypersensitivity
  DIS1KZD2: Hyperkalemia
• ICD Code:
  ICD-11: ICD-11: 5C76
  ICD-10: ICD-10: E87.5
  Expand ICD-11: '5C76
  Expand ICD-10: 'E87.5
• Disease Identifiers:
  MESH ID: D006947
  MedGen ID: 5691
  HPO ID: HP:0002153
  SNOMED CT ID: 14140009

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 2 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Patiromer calcium	DMMIQ20	Approved	NA	[1]
Sodium zirconium cyclosilicate	DMCSLZ4	Approved	NA	[2]

This Disease is Treated as An Indication in 1 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
PF-06678552	DMHQG52	Phase 1	NA	[3]

This Disease is Treated as An Indication in 1 Investigative Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
ZS-9	DM1QXMQ	Investigative	NA	[4]

Molecular Interaction Atlas (MIA) of This Disease

References

• [1] ClinicalTrials.gov (NCT01810939) A Two-Part, Single-Blind, Phase 3 Study Evaluating the Efficacy and Safety of Patiromer for the Treatment of Hyperkalemia. U.S. National Institutes of Health.
• [2] 2018 FDA drug approvals.Nat Rev Drug Discov. 2019 Feb;18(2):85-89.
• [3] ClinicalTrials.gov (NCT02079922) A Multiple Dose Study Of PF-06678552 In Healthy Subjects. U.S. National Institutes of Health.
• [4] The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.