Details of the Drug

General Information of Drug (ID: DMCZAJW)

Drug Name

Garnocestim

Synonyms

SB-251353

Indication

Disease Entry	ICD 11	Status	REF
Bone marrow transplantation	QB63.6	Discontinued in Phase 1	[1]
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Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
C-X-C chemokine receptor type 4 (CXCR4)	TTBID49	CXCR4_HUMAN	Modulator	[2]

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Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Bone marrow transplantation

ICD Disease Classification

QB63.6

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
C-X-C chemokine receptor type 4 (CXCR4)	DTT	CXCR4	7.10E-15	-0.4	-0.69

Molecular Expression Atlas (MEA)

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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010770)
2	CN patent application no. 101094684, With the combination of chemokine activation progenitor cells/stem cells.