General Information of Drug (ID: DMD60BA)

Drug Name
ISIS 140153
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Antisense drug
Sequence
TCCAGGTGCCCCTGGCCCAC
Cross-matching ID
TTD ID
D0A9LB

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
SOAT2 messenger RNA (SOAT2 mRNA) TTAK0IN SOAT2_HUMAN Not Available [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
SOAT2 messenger RNA (SOAT2 mRNA) DTT SOAT2 9.90E-02 -0.07 -0.27
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 US patent application no. 7,202,357, Antisense modulation of acyl CoA cholesterol acyltransferase-2 expression.