Details of the Drug

General Information of Drug (ID: DMDCCPC)

Drug Name

Emricasan

Synonyms

Emricasan; 254750-02-2; IDN-6556; PF-03491390; UNII-P0GMS9N47Q; (S)-3-((S)-2-(2-(2-TERT-BUTYLPHENYLAMINO)-2-OXOACETAMIDO)PROPANAMIDO)-4-OXO-5-(2,3,5,6-TETRAFLUOROPHENOXY)PENTANOIC ACID; P0GMS9N47Q; (S)-3-((S)-2-(2-((2-(tert-Butyl)phenyl)amino)-2-oxoacetamido)propanamido)-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic acid; PF 03491390; Emricasan [USAN:INN]; Emricasan (USAN/INN); SCHEMBL3288801; GTPL6508; CHEMBL197672; DTXSID10180160; MolPort-027-835-564; C26H27F4N3O7; BCP07463; IDN 6556; EX-A1659; s7775; 2073AB; ZINC14191207

Indication

Disease Entry	ICD 11	Status	REF
Hepatic fibrosis	DB93.0	Phase 2	[1]
Liver cirrhosis	DB93.1	Phase 2	[2]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C26H27F4N3O7
Canonical SMILES: CC(C(=O)NC(CC(=O)O)C(=O)COC1=C(C(=CC(=C1F)F)F)F)NC(=O)C(=O)NC2=CC=CC=C2C(C)(C)C
InChI: 1S/C26H27F4N3O7/c1-12(31-24(38)25(39)32-16-8-6-5-7-13(16)26(2,3)4)23(37)33-17(10-19(35)36)18(34)11-40-22-20(29)14(27)9-15(28)21(22)30/h5-9,12,17H,10-11H2,1-4H3,(H,31,38)(H,32,39)(H,33,37)(H,35,36)/t12-,17-/m0/s1
InChIKey: SCVHJVCATBPIHN-SJCJKPOMSA-N

Cross-matching ID

PubChem CID: 12000240
CAS Number: 254750-02-2
TTD ID: D04NAQ

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6508).
2	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)